Jens Marc Titze, M.D.

Associate Professor

jens.m.titze@vanderbilt.edu
Faculty Appointments
Associate Professor of Medicine
Education
M.D., Freie Universitat Berlin , Berlin, Germany
Publications
Schmieder R, Ott C, Linz P, Jumar A, Friedrich S, Titze J, Hammon M, Uder M, Kistner I. OS 12-03 SGLT-2-INHIBITION WITH DAPAGLIFLOZIN REDUCES TISSUE SODIUM CONTENT. J. Hypertens. 2016 Sep; 34 Suppl 1: e76. PMID: 27643373, PII: 00004872-201609001-00181, DOI: 10.1097/01.hjh.0000500051.20830.98, ISSN: 1473-5598.

Schmieder R, Ott C, Linz P, Jumar A, Friedrich S, Titze J, Hammon M, Uder M, Kistner I. OS 12-03 SGLT-2-INHIBITION WITH DAPAGLIFLOZIN REDUCES TISSUE SODIUM CONTENT. J. Hypertens. 2016 Sep; 34 Suppl 1: e76. PMID: 27643373, PII: 00004872-201609001-00181, DOI: 10.1097/01.hjh.0000500051.20830.98, ISSN: 1473-5598.

Schmieder R, Ott C, Linz P, Jumar A, Friedrich S, Titze J, Hammon M, Uder M, Kistner I. OS 12-03 SGLT-2-INHIBITION WITH DAPAGLIFLOZIN REDUCES TISSUE SODIUM CONTENT. J. Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book: e76. PMID: 27753976, PII: 00004872-201609001-00179, DOI: 10.1097/01.hjh.0000500051.20830.98, ISSN: 1473-5598.

Oh YS, Appel LJ, Galis ZS, Hafler DA, He J, Hernandez AL, Joe B, Karumanchi SA, Maric-Bilkan C, Mattson D, Mehta NN, Randolph G, Ryan M, Sandberg K, Titze J, Tolunay E, Toney GM, Harrison DG. National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness: Building on the Current Scientific Evidence. Hypertension [print-electronic]. 2016 Aug; 68(2): 281-8. PMID: 27324228, PMCID: PMC4945367, PII: HYPERTENSIONAHA.116.07415, DOI: 10.1161/HYPERTENSIONAHA.116.07415, ISSN: 1524-4563.

Oh YS, Appel LJ, Galis ZS, Hafler DA, He J, Hernandez AL, Joe B, Karumanchi SA, Maric-Bilkan C, Mattson D, Mehta NN, Randolph G, Ryan M, Sandberg K, Titze J, Tolunay E, Toney GM, Harrison DG. National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness: Building on the Current Scientific Evidence. Hypertension [print-electronic]. 2016 Aug; 68(2): 281-8. PMID: 27324228, PMCID: PMC4945367, PII: HYPERTENSIONAHA.116.07415, DOI: 10.1161/HYPERTENSIONAHA.116.07415, ISSN: 1524-4563.

Laffer CL, Scott RC, Titze JM, Luft FC, Elijovich F. Hemodynamics and Salt-and-Water Balance Link Sodium Storage and Vascular Dysfunction in Salt-Sensitive Subjects. Hypertension [print-electronic]. 2016 Jul; 68(1): 195-203. PMID: 27160204, PMCID: PMC4900938, PII: HYPERTENSIONAHA.116.07289, DOI: 10.1161/HYPERTENSIONAHA.116.07289, ISSN: 1524-4563.

Birukov A, Rakova N, Lerchl K, Engberink RH, Johannes B, Wabel P, Moissl U, Rauh M, Luft FC, Titze J. Ultra-long-term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion. Am. J. Clin. Nutr [print-electronic]. 2016 Jul; 104(1): 49-57. PMID: 27225435, PMCID: PMC4919532, PII: ajcn.116.132951, DOI: 10.3945/ajcn.116.132951, ISSN: 1938-3207.

Titze J, Rakova N, Kopp C, Dahlmann A, Jantsch J, Luft FC. Balancing wobbles in the body sodium. Nephrol. Dial. Transplant [print-electronic]. 2016 Jul; 31(7): 1078-81. PMID: 26410883, PMCID: PMC4917061, PII: gfv343, DOI: 10.1093/ndt/gfv343, ISSN: 1460-2385.

Birukov A, Rakova N, Lerchl K, Engberink RH, Johannes B, Wabel P, Moissl U, Rauh M, Luft FC, Titze J. Ultra-long-term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion. Am. J. Clin. Nutr [print-electronic]. 2016 Jul; 104(1): 49-57. PMID: 27225435, PMCID: PMC4919532, PII: ajcn.116.132951, DOI: 10.3945/ajcn.116.132951, ISSN: 1938-3207.

Titze J, Rakova N, Kopp C, Dahlmann A, Jantsch J, Luft FC. Balancing wobbles in the body sodium. Nephrol. Dial. Transplant [print-electronic]. 2016 Jul; 31(7): 1078-81. PMID: 26410883, PMCID: PMC4917061, PII: gfv343, DOI: 10.1093/ndt/gfv343, ISSN: 1460-2385.

Schatz V, Neubert P, Schröder A, Binger K, Gebhard M, Müller DN, Luft FC, Titze J, Jantsch J. Elementary immunology: Na(+) as a regulator of immunity. Pediatr. Nephrol [print-electronic]. 2016 Feb 2/26/2016; PMID: 26921211, PII: 10.1007/s00467-016-3349-x, DOI: 10.1007/s00467-016-3349-x, ISSN: 1432-198X.

Schatz V, Neubert P, Schröder A, Binger K, Gebhard M, Müller DN, Luft FC, Titze J, Jantsch J. Elementary immunology: Na(+) as a regulator of immunity. Pediatr. Nephrol [print-electronic]. 2016 Feb 2/26/2016; PMID: 26921211, PII: 10.1007/s00467-016-3349-x, DOI: 10.1007/s00467-016-3349-x, ISSN: 1432-198X.

Dahlmann A, Kopp C, Linz P, Cavallaro A, Seuss H, Eckardt KU, Luft FC, Titze J, Uder M, Hammon M. Quantitative assessment of muscle injury by (23)Na magnetic resonance imaging. Springerplus. 2016; 5(1): 661. PMID: 27347460, PMCID: PMC4899351, PII: 2193, DOI: 10.1186/s40064-016-2193-6.

Johnson RS, Titze J, Weller R. Cutaneous control of blood pressure. Curr. Opin. Nephrol. Hypertens. 2016 Jan; 25(1): 11-5. PMID: 26625865, DOI: 10.1097/MNH.0000000000000188, ISSN: 1473-6543.

Dahlmann A, Kopp C, Linz P, Cavallaro A, Seuss H, Eckardt KU, Luft FC, Titze J, Uder M, Hammon M. Quantitative assessment of muscle injury by (23)Na magnetic resonance imaging. Springerplus. 2016; 5(1): 661. PMID: 27347460, PMCID: PMC4899351, PII: 2193, DOI: 10.1186/s40064-016-2193-6.

Johnson RS, Titze J, Weller R. Cutaneous control of blood pressure. Curr. Opin. Nephrol. Hypertens. 2016 Jan; 25(1): 11-5. PMID: 26625865, DOI: 10.1097/MNH.0000000000000188, ISSN: 1473-6543.

Speed JS, Heimlich JB, Hyndman KA, Fox BM, Patel V, Yanagisawa M, Pollock JS, Titze JM, Pollock DM. Endothelin-1 as a master regulator of whole-body Na+ homeostasis. FASEB J [print-electronic]. 2015 Dec; 29(12): 4937-44. PMID: 26268928, PMCID: PMC4653060, PII: fj.15-276584, DOI: 10.1096/fj.15-276584, ISSN: 1530-6860.

Lerchl K, Rakova N, Dahlmann A, Rauh M, Goller U, Basner M, Dinges DF, Beck L, Agureev A, Larina I, Baranov V, Morukov B, Eckardt KU, Vassilieva G, Wabel P, Vienken J, Kirsch K, Johannes B, Krannich A, Luft FC, Titze J. Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment. Hypertension [print-electronic]. 2015 Oct; 66(4): 850-7. PMID: 26259596, PMCID: PMC4567387, PII: HYPERTENSIONAHA.115.05851, DOI: 10.1161/HYPERTENSIONAHA.115.05851, ISSN: 1524-4563.

Lerchl K, Rakova N, Dahlmann A, Rauh M, Goller U, Basner M, Dinges DF, Beck L, Agureev A, Larina I, Baranov V, Morukov B, Eckardt KU, Vassilieva G, Wabel P, Vienken J, Kirsch K, Johannes B, Krannich A, Luft FC, Titze J. Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment. Hypertension [print-electronic]. 2015 Oct; 66(4): 850-7. PMID: 26259596, PMCID: PMC4567387, PII: HYPERTENSIONAHA.115.05851, DOI: 10.1161/HYPERTENSIONAHA.115.05851, ISSN: 1524-4563.

Hammon M, Grossmann S, Linz P, Kopp C, Dahlmann A, Janka R, Cavallaro A, Uder M, Titze J. 3 Tesla (23)Na magnetic resonance imaging during aerobic and anaerobic exercise. Acad Radiol [print-electronic]. 2015 Sep; 22(9): 1181-90. PMID: 26152501, PII: S1076-6332(15)00252-4, DOI: 10.1016/j.acra.2015.06.005, ISSN: 1878-4046.

Hammon M, Grossmann S, Linz P, Kopp C, Dahlmann A, Janka R, Cavallaro A, Uder M, Titze J. 3 Tesla (23)Na magnetic resonance imaging during aerobic and anaerobic exercise. Acad Radiol [print-electronic]. 2015 Sep; 22(9): 1181-90. PMID: 26152501, PII: S1076-6332(15)00252-4, DOI: 10.1016/j.acra.2015.06.005, ISSN: 1878-4046.

Yi B, Titze J, Rykova M, Feuerecker M, Vassilieva G, Nichiporuk I, Schelling G, Morukov B, Choukèr A. Effects of dietary salt levels on monocytic cells and immune responses in healthy human subjects: a longitudinal study. Transl Res [print-electronic]. 2015 Jul; 166(1): 103-10. PMID: 25497276, PII: S1931-5244(14)00423-X, DOI: 10.1016/j.trsl.2014.11.007, ISSN: 1878-1810.

Yi B, Titze J, Rykova M, Feuerecker M, Vassilieva G, Nichiporuk I, Schelling G, Morukov B, Choukèr A. Effects of dietary salt levels on monocytic cells and immune responses in healthy human subjects: a longitudinal study. Transl Res [print-electronic]. 2015 Jul; 166(1): 103-10. PMID: 25497276, PII: S1931-5244(14)00423-X, DOI: 10.1016/j.trsl.2014.11.007, ISSN: 1878-1810.

Jantsch J, Schatz V, Friedrich D, Schröder A, Kopp C, Siegert I, Maronna A, Wendelborn D, Linz P, Binger KJ, Gebhardt M, Heinig M, Neubert P, Fischer F, Teufel S, David JP, Neufert C, Cavallaro A, Rakova N, Küper C, Beck FX, Neuhofer W, Muller DN, Schuler G, Uder M, Bogdan C, Luft FC, Titze J. Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense. Cell Metab. 2015 Mar 3/3/2015; 21(3): 493-501. PMID: 25738463, PMCID: PMC4350016, PII: S1550-4131(15)00055-8, DOI: 10.1016/j.cmet.2015.02.003, ISSN: 1932-7420.

Jantsch J, Schatz V, Friedrich D, Schröder A, Kopp C, Siegert I, Maronna A, Wendelborn D, Linz P, Binger KJ, Gebhardt M, Heinig M, Neubert P, Fischer F, Teufel S, David JP, Neufert C, Cavallaro A, Rakova N, Küper C, Beck FX, Neuhofer W, Muller DN, Schuler G, Uder M, Bogdan C, Luft FC, Titze J. Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense. Cell Metab. 2015 Mar 3/3/2015; 21(3): 493-501. PMID: 25738463, PMCID: PMC4350016, PII: S1550-4131(15)00055-8, DOI: 10.1016/j.cmet.2015.02.003, ISSN: 1932-7420.

Hofmeister LH, Perisic S, Titze J. Tissue sodium storage: evidence for kidney-like extrarenal countercurrent systems?. Pflugers Arch [print-electronic]. 2015 Mar; 467(3): 551-8. PMID: 25600900, PMCID: PMC4340694, DOI: 10.1007/s00424-014-1685-x, ISSN: 1432-2013.

Hofmeister LH, Perisic S, Titze J. Tissue sodium storage: evidence for kidney-like extrarenal countercurrent systems?. Pflugers Arch [print-electronic]. 2015 Mar; 467(3): 551-8. PMID: 25600900, PMCID: PMC4340694, DOI: 10.1007/s00424-014-1685-x, ISSN: 1432-2013.

Dahlmann A, Dörfelt K, Eicher F, Linz P, Kopp C, Mössinger I, Horn S, Büschges-Seraphin B, Wabel P, Hammon M, Cavallaro A, Eckardt KU, Kotanko P, Levin NW, Johannes B, Uder M, Luft FC, Müller DN, Titze JM. Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients. Kidney Int [print-electronic]. 2015 Feb; 87(2): 434-41. PMID: 25100048, PII: ki2014269, DOI: 10.1038/ki.2014.269, ISSN: 1523-1755.

Hammon M, Grossmann S, Linz P, Kopp C, Dahlmann A, Garlichs C, Janka R, Cavallaro A, Luft FC, Uder M, Titze J. 23Na Magnetic Resonance Imaging of the Lower Leg of Acute Heart Failure Patients during Diuretic Treatment. PLoS ONE. 2015; 10(10): e0141336. PMID: 26501774, PMCID: PMC4621023, PII: PONE-D-15-29049, DOI: 10.1371/journal.pone.0141336, ISSN: 1932-6203.

Titze J. A different view on sodium balance. Curr. Opin. Nephrol. Hypertens. 2015 Jan; 24(1): 14-20. PMID: 25470013, PII: 00041552-201501000-00004, DOI: 10.1097/MNH.0000000000000085, ISSN: 1473-6543.

Hammon M, Grossmann S, Linz P, Kopp C, Dahlmann A, Garlichs C, Janka R, Cavallaro A, Luft FC, Uder M, Titze J. 23Na Magnetic Resonance Imaging of the Lower Leg of Acute Heart Failure Patients during Diuretic Treatment. PLoS ONE. 2015; 10(10): e0141336. PMID: 26501774, PMCID: PMC4621023, PII: PONE-D-15-29049, DOI: 10.1371/journal.pone.0141336, ISSN: 1932-6203.

Titze J. A different view on sodium balance. Curr. Opin. Nephrol. Hypertens. 2015 Jan; 24(1): 14-20. PMID: 25470013, PII: 00041552-201501000-00004, DOI: 10.1097/MNH.0000000000000085, ISSN: 1473-6543.

Titze J, Müller DN, Luft FC. Taking another "look" at sodium [editorial]. Can J Cardiol [print-electronic]. 2014 May; 30(5): 473-5. PMID: 24630375, PII: S0828-282X(14)00085-3, DOI: 10.1016/j.cjca.2014.02.006, ISSN: 1916-7075.

Titze J, Müller DN, Luft FC. Taking another "look" at sodium [editorial]. Can J Cardiol [print-electronic]. 2014 May; 30(5): 473-5. PMID: 24630375, PII: S0828-282X(14)00085-3, DOI: 10.1016/j.cjca.2014.02.006, ISSN: 1916-7075.

Titze J, Dahlmann A, Lerchl K, Kopp C, Rakova N, Schröder A, Luft FC. Spooky sodium balance. Kidney Int [print-electronic]. 2014 Apr; 85(4): 759-67. PMID: 24107854, PII: S0085-2538(15)56280-7, DOI: 10.1038/ki.2013.367, ISSN: 1523-1755.

Titze J, Dahlmann A, Lerchl K, Kopp C, Rakova N, Schröder A, Luft FC. Spooky sodium balance. Kidney Int [print-electronic]. 2014 Apr; 85(4): 759-67. PMID: 24107854, PII: S0085-2538(15)56280-7, DOI: 10.1038/ki.2013.367, ISSN: 1523-1755.

Titze J. Sodium balance is not just a renal affair. Curr. Opin. Nephrol. Hypertens. 2014 Mar; 23(2): 101-5. PMID: 24401786, PMCID: PMC4932095, DOI: 10.1097/01.mnh.0000441151.55320.c3, ISSN: 1473-6543.

Titze J. Sodium balance is not just a renal affair. Curr. Opin. Nephrol. Hypertens. 2014 Mar; 23(2): 101-5. PMID: 24401786, PMCID: PMC4932095, DOI: 10.1097/01.mnh.0000441151.55320.c3, ISSN: 1473-6543.

Jantsch J, Binger KJ, Müller DN, Titze J. Macrophages in homeostatic immune function. Front Physiol. 2014; 5: 146. PMID: 24847274, PMCID: PMC4017126, DOI: 10.3389/fphys.2014.00146.

Jantsch J, Binger KJ, Müller DN, Titze J. Macrophages in homeostatic immune function. Front Physiol. 2014; 5: 146. PMID: 24847274, PMCID: PMC4017126, DOI: 10.3389/fphys.2014.00146.

Titze J. Interstitial fluid homeostasis and pressure: news from the black box. Kidney Int. 2013 Nov; 84(5): 869-71. PMID: 24172732, PII: S0085-2538(15)56082-1, DOI: 10.1038/ki.2013.287, ISSN: 1523-1755.

Titze J. Interstitial fluid homeostasis and pressure: news from the black box. Kidney Int. 2013 Nov; 84(5): 869-71. PMID: 24172732, PII: S0085-2538(15)56082-1, DOI: 10.1038/ki.2013.287, ISSN: 1523-1755.

Kopp C, Linz P, Dahlmann A, Hammon M, Jantsch J, Müller DN, Schmieder RE, Cavallaro A, Eckardt KU, Uder M, Luft FC, Titze J. 23Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients. Hypertension [print-electronic]. 2013 Mar; 61(3): 635-40. PMID: 23339169, PII: HYPERTENSIONAHA.111.00566, DOI: 10.1161/HYPERTENSIONAHA.111.00566, ISSN: 1524-4563.

Kopp C, Linz P, Dahlmann A, Hammon M, Jantsch J, Müller DN, Schmieder RE, Cavallaro A, Eckardt KU, Uder M, Luft FC, Titze J. 23Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients. Hypertension [print-electronic]. 2013 Mar; 61(3): 635-40. PMID: 23339169, PII: HYPERTENSIONAHA.111.00566, DOI: 10.1161/HYPERTENSIONAHA.111.00566, ISSN: 1524-4563.

Harrison DG, Marvar PJ, Titze JM. Vascular inflammatory cells in hypertension. Front Physiol. 2012; 3: 128. PMID: 22586409, PMCID: PMC3345946, DOI: 10.3389/fphys.2012.00128, ISSN: 1664-042X.

Harrison DG, Marvar PJ, Titze JM. Vascular inflammatory cells in hypertension. Front Physiol. 2012; 3: 128. PMID: 22586409, PMCID: PMC3345946, DOI: 10.3389/fphys.2012.00128, ISSN: 1664-042X.