Douglas C. Heimburger, M.D.

Professor

douglas.heimburger@vanderbilt.edu

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Faculty Appointments
Professor of Medicine
Education
M.S., University of Alabama, Tuscaloosa, AlabamaM.D., Medicine , Vanderbilt University, Nashville, TennesseeB.S., Harding College, Searcy, Arkansas
Office Address
Vanderbilt Institute for Global Health
Suite 750
2525 West End Avenue
Nashville, TN 37203
Clinical Research Keywords
Global Health, Global Health Education, Nutrition, Epidemiology, HIV/AIDS
Publications
Woodd SL, Kelly P, Koethe JR, Praygod G, Rehman AM, Chisenga M, Siame J, Heimburger DC, Friis H, Filteau S. Risk factors for mortality among malnourished HIV-infected adults eligible for antiretroviral therapy. BMC Infect. Dis. 2016 Oct 10/12/2016; 16(1): 562. PMID: 27733134, PMCID: PMC5062813, PII: 10.1186/s12879-016-1894-3, DOI: 10.1186/s12879-016-1894-3, ISSN: 1471-2334.

Koethe JR, Heimburger DC, PrayGod G, Filteau S. From Wasting to Obesity: The Contribution of Nutritional Status to Immune Activation in HIV Infection. J. Infect. Dis. 2016 Oct 10/1/2016; 214 Suppl 2: S75-82. PMID: 27625434, PMCID: PMC5021242, PII: jiw286, DOI: 10.1093/infdis/jiw286, ISSN: 1537-6613.

Zunt JR, Chi BH, Heimburger DC, Cohen CR, Strathdee S, Hobbs N, Thomas Y, Bale K, Salisbury K, Hernandez MT, Riley LW, Vermund SH, van der Horst C. The National Institutes of Health Fogarty International Center Global Health Scholars and Fellows Program: Collaborating Across Five Consortia to Strengthen Research Training. Am. J. Trop. Med. Hyg [print-electronic]. 2016 Sep 9/7/2016; 95(3): 728-34. PMID: 27382074, PMCID: PMC5014285, PII: ajtmh.16-0190, DOI: 10.4269/ajtmh.16-0190, ISSN: 1476-1645.

PrayGod G, Blevins M, Woodd S, Rehman AM, Jeremiah K, Friis H, Kelly P, Changalucha J, Heimburger DC, Filteau S, Koethe JR. A longitudinal study of systemic inflammation and recovery of lean body mass among malnourished HIV-infected adults starting antiretroviral therapy in Tanzania and Zambia. Eur J Clin Nutr [print-electronic]. 2016 Apr; 70(4): 499-504. PMID: 26785764, PII: ejcn2015221, DOI: 10.1038/ejcn.2015.221, ISSN: 1476-5640.

Heimburger DC, Carothers CL, Blevins M, Warner TL, Vermund SH. Impact of Global Health Research Training on Scholarly Productivity: The Fogarty International Clinical Research Scholars and Fellows Program. Am. J. Trop. Med. Hyg [print-electronic]. 2015 Dec; 93(6): 1201-7. PMID: 26371155, PMCID: PMC4674235, PII: ajtmh.15-0432, DOI: 10.4269/ajtmh.15-0432, ISSN: 1476-1645.

Heimburger DC, Carothers CL, Blevins M, Warner TL, Vermund SH. Impact of Global Health Research Training on Career Trajectories: The Fogarty International Clinical Research Scholars and Fellows Program. Am. J. Trop. Med. Hyg [print-electronic]. 2015 Sep; 93(3): 655-61. PMID: 26195466, PMCID: PMC4559713, PII: ajtmh.14-0705, DOI: 10.4269/ajtmh.14-0705, ISSN: 1476-1645.

Bestawros M, Chidumayo T, Blevins M, Canipe A, Bala J, Kelly P, Filteau S, Shepherd BE, Heimburger DC, Koethe JR. Increased systemic inflammation is associated with cardiac and vascular dysfunction over the first 12 weeks of antiretroviral therapy among undernourished, HIV-infected adults in Southern Africa. J AIDS Clin Res. 2015 Mar; 6(3): PMID: 26038711, PMCID: PMC4450092, DOI: 10.4172/2155-6113.1000431.

Nyirenda CK, Kabagambe EK, Koethe JR, Kiage JN, Chi BH, Musonda P, Blevins M, Bosire CN, Tsai MY, Heimburger DC. Plasma Fatty Acids in Zambian Adults with HIV/AIDS: Relation to Dietary Intake and Cardiovascular Risk Factors. J Nutr Metab [print-electronic]. 2015; 2015: 635817. PMID: 26161268, PMCID: PMC4460253, DOI: 10.1155/2015/635817, ISSN: 2090-0724.

Heimburger DC, Carothers CL, Vermund SH. In response [letter]. Am. J. Trop. Med. Hyg. 2014 Dec; 91(6): 1282. PMID: 25473066, PMCID: PMC4257660, PII: 91/6/1282, DOI: 10.4269/ajtmh.14-0479, ISSN: 1476-1645.

Bearnot B, Coria A, Barnett BS, Clark EH, Gartland MG, Jaganath D, Mendenhall E, Seu L, Worjoloh AG, Carothers CL, Vermund SH, Heimburger DC. Global health research in narrative: a qualitative look at the FICRS-F experience. Am. J. Trop. Med. Hyg [print-electronic]. 2014 Nov; 91(5): 863-8. PMID: 25246694, PMCID: PMC4228876, PII: ajtmh.13-0481, DOI: 10.4269/ajtmh.13-0481, ISSN: 1476-1645.

Andrews B, Muchemwa L, Kelly P, Lakhi S, Heimburger DC, Bernard GR. Simplified severe sepsis protocol: a randomized controlled trial of modified early goal-directed therapy in Zambia. Crit. Care Med. 2014 Nov; 42(11): 2315-24. PMID: 25072757, PMCID: PMC4199893, DOI: 10.1097/CCM.0000000000000541, ISSN: 1530-0293.

Canipe A, Chidumayo T, Blevins M, Bestawros M, Bala J, Kelly P, Filteau S, Shepherd BE, Heimburger DC, Koethe JR. A 12 week longitudinal study of microbial translocation and systemic inflammation in undernourished HIV-infected Zambians initiating antiretroviral therapy. BMC Infect. Dis. 2014 Sep 9/29/2014; 14: 521. PMID: 25266928, PMCID: PMC4261887, PII: 1471-2334-14-521, DOI: 10.1186/1471-2334-14-521, ISSN: 1471-2334.

Heimburger DC, Warner TL, Carothers CL, Blevins M, Thomas Y, Gardner P, Primack A, Vermund SH. Recruiting post-doctoral fellows into global health research: selecting NIH Fogarty International Clinical Research Fellows. Am. J. Trop. Med. Hyg [print-electronic]. 2014 Aug; 91(2): 219-24. PMID: 24865678, PMCID: PMC4125240, PII: ajtmh.13-0741, DOI: 10.4269/ajtmh.13-0741, ISSN: 1476-1645.

Carothers CL, Heimburger DC, Schlachter S, Gardner P, Primack A, Warner TL, Vermund SH. Training programs within global networks: lessons learned in the Fogarty International Clinical Research Scholars and Fellows Program. Am. J. Trop. Med. Hyg [print-electronic]. 2014 Jan; 90(1): 173-9. PMID: 24297815, PMCID: PMC3886417, PII: ajtmh.12-0512, DOI: 10.4269/ajtmh.12-0512, ISSN: 1476-1645.

Slone JS, Chunda-Liyoka C, Perez M, Mutalima N, Newton R, Chintu C, Kankasa C, Chipeta J, Heimburger DC, Vermund SH, Friedman DL. Pediatric malignancies, treatment outcomes and abandonment of pediatric cancer treatment in Zambia. PLoS ONE. 2014; 9(2): e89102. PMID: 24586527, PMCID: PMC3931678, PII: PONE-D-13-40568, DOI: 10.1371/journal.pone.0089102, ISSN: 1932-6203.

Heimburger DC, Warner TL, Carothers CL, Blevins M, Thomas Y, Gardner P, Primack A, Vermund SH. Recruiting trainees for a global health research workforce: the National Institutes of Health Fogarty International Clinical Research Scholars Program selection process. Am. J. Trop. Med. Hyg [print-electronic]. 2013 Aug; 89(2): 281-7. PMID: 23798584, PMCID: PMC3741249, PII: ajtmh.12-0677, DOI: 10.4269/ajtmh.12-0677, ISSN: 1476-1645.

Kiage JN, Heimburger DC, Nyirenda CK, Wellons MF, Bagchi S, Chi BH, Koethe JR, Arnett DK, Kabagambe EK. Cardiometabolic risk factors among HIV patients on antiretroviral therapy. Lipids Health Dis. 2013 Apr 4/10/2013; 12: 50. PMID: 23575345, PMCID: PMC3641018, PII: 1476-511X-12-50, DOI: 10.1186/1476-511X-12-50, ISSN: 1476-511X.

Koethe JR, Blevins M, Bosire C, Nyirenda C, Kabagambe EK, Mwango A, Kasongo W, Zulu I, Shepherd BE, Heimburger DC. Self-reported dietary intake and appetite predict early treatment outcome among low-BMI adults initiating HIV treatment in sub-Saharan Africa. Public Health Nutr [print-electronic]. 2013 Mar; 16(3): 549-58. PMID: 22691872, PMCID: PMC3772135, PII: S1368980012002960, DOI: 10.1017/S1368980012002960, ISSN: 1475-2727.

Koethe JR, Blevins M, Nyirenda CK, Kabagambe EK, Chiasera JM, Shepherd BE, Zulu I, Heimburger DC. Serum Phosphate Predicts Early Mortality among Underweight Adults Starting ART in Zambia: A Novel Context for Refeeding Syndrome?. J Nutr Metab [print-electronic]. 2013; 2013: 545439. PMID: 23691292, PMCID: PMC3652146, DOI: 10.1155/2013/545439, ISSN: 2090-0724.

Heimburger RF, Heimburger DC. Reflections on a career in neurosurgery. Surg Neurol Int. 2013; 4: 89. PMID: 23956932, PMCID: PMC3740609, PII: SNI-4-89, DOI: 10.4103/2152-7806.114812, ISSN: 2229-5097.

Heimburger DC, Carothers CL, Gardner P, Primack A, Warner TL, Vermund SH. Nurturing the global workforce in clinical research: the National Institutes of Health Fogarty International Clinical Scholars and Fellows Program. Am. J. Trop. Med. Hyg. 2011 Dec; 85(6): 971-8. PMID: 22144429, PMCID: PMC3225173, PII: 85/6/971, DOI: 10.4269/ajtmh.2011.11-0141, ISSN: 1476-1645.

Koethe JR, Blevins M, Nyirenda C, Kabagambe EK, Shepherd BE, Wester CW, Zulu I, Chiasera JM, Mulenga LB, Mwango A, Heimburger DC. Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia. J Int AIDS Soc. 2011; 14: 19. PMID: 21477359, PMCID: PMC3094357, PII: 1758-2652-14-19, DOI: 10.1186/1758-2652-14-19, ISSN: 1758-2652.

Heimburger DC, McClave SA, Gramlich LM, Merritt R. The Intersociety Professional Nutrition Education Consortium and American Board of Physician Nutrition Specialists: what have we learned?. JPEN J Parenter Enteral Nutr. 2010 Nov; 34(6 Suppl): 21S-9S. PMID: 21149832, PII: 34/6_suppl/21S, DOI: 10.1177/0148607110372393, ISSN: 0148-6071.

Locher JL, Robinson CO, Bailey FA, Carroll WR, Heimburger DC, Saif MW, Tajeu G, Ritchie CS. Disruptions in the organization of meal preparation and consumption among older cancer patients and their family caregivers. Psychooncology. 2010 Sep; 19(9): 967-74. PMID: 19950254, PMCID: PMC2888857, DOI: 10.1002/pon.1656, ISSN: 1099-1611.

Koethe JR, Heimburger DC. Nutritional aspects of HIV-associated wasting in sub-Saharan Africa. Am. J. Clin. Nutr [print-electronic]. 2010 Apr; 91(4): 1138S-1142S. PMID: 20147470, PMCID: PMC2844686, PII: ajcn.2010.28608D, DOI: 10.3945/ajcn.2010.28608D, ISSN: 1938-3207.

Heimburger DC, Koethe JR, Nyirenda C, Bosire C, Chiasera JM, Blevins M, Munoz AJ, Shepherd BE, Potter D, Zulu I, Chisembele-Taylor A, Chi BH, Stringer JS, Kabagambe EK. Serum phosphate predicts early mortality in adults starting antiretroviral therapy in Lusaka, Zambia: a prospective cohort study. PLoS ONE. 2010; 5(5): e10687. PMID: 20502700, PMCID: PMC2872675, DOI: 10.1371/journal.pone.0010687, ISSN: 1932-6203.

Jensen GL, Bistrian B, Roubenoff R, Heimburger DC. Malnutrition syndromes: a conundrum vs continuum. JPEN J Parenter Enteral Nutr. 2009 Nov; 33(6): 710-6. PMID: 19892905, PII: 33/6/710, DOI: 10.1177/0148607109344724, ISSN: 0148-6071.

Koethe JR, Chi BH, Megazzini KM, Heimburger DC, Stringer JS. Macronutrient supplementation for malnourished HIV-infected adults: a review of the evidence in resource-adequate and resource-constrained settings. Clin. Infect. Dis. 2009 Sep 9/1/2009; 49(5): 787-98. PMID: 19624276, PMCID: PMC3092426, DOI: 10.1086/605285, ISSN: 1537-6591.

Locher JL, Robinson CO, Bailey FA, Carroll WR, Heimburger DC, Magnuson JS, Saif MW, Ritchie CS. The contribution of social factors to undereating in older adults with cancer. J Support Oncol. 2009 Sep; 7(5): 168-73. PMID: 19831160, PMCID: PMC4077780, ISSN: 1544-6794.

Piyathilake CJ, Macaluso M, Alvarez RD, Bell WC, Heimburger DC, Partridge EE. Lower risk of cervical intraepithelial neoplasia in women with high plasma folate and sufficient vitamin B12 in the post-folic acid fortification era. Cancer Prev Res (Phila) [print-electronic]. 2009 Jul; 2(7): 658-64. PMID: 19542191, PII: 1940-6207.CAPR-08-0175, DOI: 10.1158/1940-6207.CAPR-08-0175, ISSN: 1940-6215.

Butsch WS, Ard JD, Allison DB, Patki A, Henson CS, Rueger MM, Hubbert KA, Glandon GL, Heimburger DC. Effects of a reimbursement incentive on enrollment in a weight control program. Obesity (Silver Spring). 2007 Nov; 15(11): 2733-8. PMID: 18070764, PII: 15/11/2733, DOI: 10.1038/oby.2007.325, ISSN: 1930-7381.

Butsch WS, Munoz AJ, Heimburger DC. Follow-up of patients with early breast cancer [letter]. N. Engl. J. Med. 2007 Sep 9/6/2007; 357(10): 1053; author reply 1053. PMID: 17823995, ISSN: 1533-4406.

Munoz AJ, Butsch WS, Morgan SL, Heimburger DC, Newton L, Clark R, Cross JM. Comment on "Nutritional gain versus financial gain: the role of metabolic carts in the surgical ICU" [letter]. J Trauma. 2007 Jun; 62(6): 1539-40; author reply 1540. PMID: 17563687, PII: 00005373-200706000-00057, DOI: 10.1097/TA.0b013e318059b5e6, ISSN: 1529-8809.

Cox TL, Malpede CZ, Desmond RA, Faulk LE, Myer RA, Henson CS, Heimburger DC, Ard JD. Physical activity patterns during weight maintenance following a low-energy density dietary intervention. Obesity (Silver Spring). 2007 May; 15(5): 1226-32. PMID: 17495199, PII: 15/5/1226, DOI: 10.1038/oby.2007.144, ISSN: 1930-7381.

Piyathilake CJ, Azrad M, Macaluso M, Johanning GL, Cornwell PE, Partridge EE, Heimburger DC. Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status. Nutrition [print-electronic]. 2007 Mar; 23(3): 229-35. PMID: 17303386, PMCID: PMC2025704, PII: S0899-9007(06)00440-0, DOI: 10.1016/j.nut.2006.12.006, ISSN: 0899-9007.

Piyathilake CJ, Macaluso M, Brill I, Heimburger DC, Partridge EE. Lower red blood cell folate enhances the HPV-16-associated risk of cervical intraepithelial neoplasia. Nutrition [print-electronic]. 2007 Mar; 23(3): 203-10. PMID: 17276035, PII: S0899-9007(06)00419-9, DOI: 10.1016/j.nut.2006.12.002, ISSN: 0899-9007.

Shikany JM, Barash J, Redden DT, Westfall AO, Heimburger DC, Henson CS, Allison DB. Divergence in popular diets relative to diets consumed by Americans, and implications for diet selection. MedGenMed. 2007; 9(3): 8. PMID: 18092015, PMCID: PMC2100078, ISSN: 1531-0132.

Greene LF, Malpede CZ, Henson CS, Hubbert KA, Heimburger DC, Ard JD. Weight maintenance 2 years after participation in a weight loss program promoting low-energy density foods. Obesity (Silver Spring). 2006 Oct; 14(10): 1795-801. PMID: 17062810, PII: 14/10/1795, DOI: 10.1038/oby.2006.207, ISSN: 1930-7381.

Heimburger DC. Training and certifying Physician Nutrition Specialists: the American Board of Physician Nutrition Specialists (ABPNS). Am. J. Clin. Nutr. 2006 Apr; 83(4): 985S-987S. PMID: 16600961, PII: 83/4/985S, ISSN: 0002-9165.

Owsley C, McGwin G, Jackson GR, Heimburger DC, Piyathilake CJ, Klein R, White MF, Kallies K. Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy. Invest. Ophthalmol. Vis. Sci. 2006 Apr; 47(4): 1310-8. PMID: 16565362, PII: 47/4/1310, DOI: 10.1167/iovs.05-1292, ISSN: 0146-0404.

Lyles TE, Desmond R, Faulk LE, Henson S, Hubbert K, Heimburger DC, Ard JD. Diet variety based on macronutrient intake and its relationship with body mass index. MedGenMed. 2006; 8(3): 39. PMID: 17406172, PMCID: PMC1781268, PII: 540875, ISSN: 1531-0132.

Shikany JM, Thomas SE, Henson CS, Redden DT, Heimburger DC. Glycemic index and glycemic load of popular weight-loss diets. MedGenMed. 2006; 8(1): 22. PMID: 16915152, PMCID: PMC1682003, PII: 518725, ISSN: 1531-0132.