Robert H. Carnahan, Ph.D.

Associate Professor

robert.carnahan@vanderbilt.edu

Visit Lab Site


Faculty Appointments
Associate Professor of Cancer Biology
Education
Ph.D., Cell Biology, Vanderbilt University, Nashville, TennesseeB.S., Biology/Psychology, Indiana University, Bloomington, Indiana
Office Address
893 PRB
438 PRB
2220 Pierce Ave
Nashville, TN 37232
Publications
Markham NO, Cooper T, Goff M, Gribben EM, Carnahan RH, Reynolds AB. Monoclonal antibodies to DIPA: a novel binding partner of p120-catenin isoform 1. Hybridoma (Larchmt). 2012 Aug; 31(4): 246-54. PMID: 22894777, PMCID: PMC3420552, DOI: 10.1089/hyb.2012.0009, ISSN: 1557-8348.

Kurley SJ, Bierie B, Carnahan RH, Lobdell NA, Davis MA, Hofmann I, Moses HL, Muller WJ, Reynolds AB. P120-catenin is essential for terminal end bud function and mammary morphogenesis. Development [print-electronic]. 2012 May; 139(10): 1754-64. PMID: 22461563, PMCID: PMC3328177, PII: dev.072769, DOI: 10.1242/dev.072769, ISSN: 1477-9129.

Akingbade D, Kingsley PJ, Shuck SC, Cooper T, Carnahan R, Szekely J, Marnett LJ. Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo. Chem. Res. Toxicol [print-electronic]. 2012 Feb 2/20/2012; 25(2): 454-61. PMID: 22211372, PMCID: PMC3285145, DOI: 10.1021/tx200494h, ISSN: 1520-5010.

Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp RD, Wilson KT, Hiebert SW, Reynolds AB, Williams CS. Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. PLoS ONE [print-electronic]. 2012; 7(12): e51205. PMID: 23251453, PMCID: PMC3521008, PII: PONE-D-12-22965, DOI: 10.1371/journal.pone.0051205, ISSN: 1932-6203.

Smith AL, Friedman DB, Yu H, Carnahan RH, Reynolds AB. ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes. PLoS ONE. 2011; 6(1): e16206. PMID: 21283770, PMCID: PMC3024417, DOI: 10.1371/journal.pone.0016206, ISSN: 1932-6203.

Carnahan RH, Rokas A, Gaucher EA, Reynolds AB. The molecular evolution of the p120-catenin subfamily and its functional associations. PLoS ONE. 2010; 5(12): e15747. PMID: 21209830, PMCID: PMC3013132, DOI: 10.1371/journal.pone.0015747, ISSN: 1932-6203.

Lund L, Dubrowski A, Carnahan H. A modular approach for training urologists in laparoscopy. BJU Int. 2007 Dec; 100(6): 1216-8. PMID: 17979919, PII: BJU7253, DOI: 10.1111/j.1464-410X.2007.07253.x, ISSN: 1464-410X.

Wildenberg GA, Dohn MR, Carnahan RH, Davis MA, Lobdell NA, Settleman J, Reynolds AB. P120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell. 2006 Dec 12/1/2006; 127(5): 1027-39. PMID: 17129786, PII: S0092-8674(06)01407-3, DOI: 10.1016/j.cell.2006.09.046, ISSN: 0092-8674.

Xia X, Carnahan RH, Vaughan MH, Wildenberg GA, Reynolds AB. P120 serine and threonine phosphorylation is controlled by multiple ligand-receptor pathways but not cadherin ligation. Exp. Cell Res [print-electronic]. 2006 Oct 10/15/2006; 312(17): 3336-48. PMID: 16935280, PII: S0014-4827(06)00274-6, DOI: 10.1016/j.yexcr.2006.07.007, ISSN: 0014-4827.

Carnahan RH, Feoktistova A, Ren L, Niessen S, Yates JR, Gould KL. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Eukaryotic Cell. 2005 Mar; 4(3): 577-87. PMID: 15755920, PMCID: PMC1087801, PII: 4/3/577, DOI: 10.1128/EC.4.3.577-587.2005, ISSN: 1535-9778.

Reynolds AB, Carnahan RH. Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancer. Semin. Cell Dev. Biol. 2004 Dec; 15(6): 657-63. PMID: 15561585, PII: S1084-9521(04)00089-8, DOI: 10.1016/j.semcdb.2004.09.003, ISSN: 1084-9521.

Carnahan RH, Gould KL. The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe. J. Cell Biol [print-electronic]. 2003 Sep 9/1/2003; 162(5): 851-62. PMID: 12939254, PMCID: PMC2172828, PII: jcb.200305012, DOI: 10.1083/jcb.200305012, ISSN: 0021-9525.

Tasto JJ, Carnahan RH, McDonald WH, Gould KL. Vectors and gene targeting modules for tandem affinity purification in Schizosaccharomyces pombe. Yeast. 2001 May; 18(7): 657-62. PMID: 11329175, DOI: 10.1002/yea.713, ISSN: 0749-503X.

Bost AG, Carnahan RH, Lu XT, Denison MR. Four proteins processed from the replicase gene polyprotein of mouse hepatitis virus colocalize in the cell periphery and adjacent to sites of virion assembly. J. Virol. 2000 Apr; 74(7): 3379-87. PMID: 10708455, PMCID: PMC111839, ISSN: 0022-538X.

Zhao G, Yeh WK, Carnahan RH, Flokowitsch J, Meier TI, Alborn WE, Becker GW, Jaskunas SR. Biochemical characterization of penicillin-resistant and -sensitive penicillin-binding protein 2x transpeptidase activities of Streptococcus pneumoniae and mechanistic implications in bacterial resistance to beta-lactam antibiotics. J. Bacteriol. 1997 Aug; 179(15): 4901-8. PMID: 9244281, PMCID: PMC179340, ISSN: 0021-9193.