John A. McPherson, M.D.

Professor

john.mcpherson@vanderbilt.edu
Faculty Appointments
Professor of Medicine
Education
M.D., David Geffen School of Medicine at UCLA, Los Angeles, CaliforniaB.A., Princeton University, Princeton, New Jersey
Office Address
1161 21st Avenue South
Nashville, TN 37232
Publications
Ladapo JA, Herman L, Weiner BH, Rhees B, Castle L, Monane M, McPherson JA. Use of a blood test incorporating age, sex, and gene expression influences medical decision-making in the evaluation of women presenting with symptoms suggestive of obstructive coronary artery disease: summary results from two ambulatory care studies in primary care. Menopause. 2015 Nov; 22(11): 1224-30. PMID: 25828395, DOI: 10.1097/GME.0000000000000443, ISSN: 1530-0374.

Kern KB, Lotun K, Patel N, Mooney MR, Hollenbeck RD, McPherson JA, McMullan PW, Unger B, Hsu CH, Seder DB, . Outcomes of Comatose Cardiac Arrest Survivors With and Without ST-Segment Elevation Myocardial Infarction: Importance of Coronary Angiography. JACC Cardiovasc Interv [print-electronic]. 2015 Jul; 8(8): 1031-40. PMID: 26117462, PII: S1936-8798(15)00679-2, DOI: 10.1016/j.jcin.2015.02.021, ISSN: 1876-7605.

Young MN, Hollenbeck RD, Pollock JS, Giuseffi JL, Wang L, Harrell FE, McPherson JA. Higher achieved mean arterial pressure during therapeutic hypothermia is not associated with neurologically intact survival following cardiac arrest. Resuscitation [print-electronic]. 2015 Mar; 88: 158-64. PMID: 25541429, PMCID: PMC4330116, PII: S0300-9572(14)00890-9, DOI: 10.1016/j.resuscitation.2014.12.008, ISSN: 1873-1570.

Young MN, Hollenbeck RD, Pollock JS, McPherson JA, Fredi JL, Piana RN, Mah ML, Fish FA, Markham L. Effectiveness of mild therapeutic hypothermia following cardiac arrest in adult patients with congenital heart disease. Am. J. Cardiol [print-electronic]. 2014 Jul 7/1/2014; 114(1): 128-30. PMID: 24819894, PII: S0002-9149(14)00969-2, DOI: 10.1016/j.amjcard.2014.04.012, ISSN: 1879-1913.

Burjek NE, Wagner CE, Hollenbeck RD, Wang L, Yu C, McPherson JA, Billings FT. Early bispectral index and sedation requirements during therapeutic hypothermia predict neurologic recovery following cardiac arrest. Crit. Care Med. 2014 May; 42(5): 1204-12. PMID: 24365859, PMCID: PMC3989405, DOI: 10.1097/CCM.0000000000000126, ISSN: 1530-0293.

Xie Y, Mintz GS, Yang J, Doi H, Iñiguez A, Dangas GD, Serruys PW, McPherson JA, Wennerblom B, Xu K, Weisz G, Stone GW, Maehara A. Clinical outcome of nonculprit plaque ruptures in patients with acute coronary syndrome in the PROSPECT study. JACC Cardiovasc Imaging [print-electronic]. 2014 Apr; 7(4): 397-405. PMID: 24631511, PII: S1936-878X(13)00897-8, DOI: 10.1016/j.jcmg.2013.10.010, ISSN: 1876-7591.

Pollock JS, Hollenbeck RD, Wang L, Janz DR, Rice TW, McPherson JA. A history of smoking is associated with improved survival in patients treated with mild therapeutic hypothermia following cardiac arrest. Resuscitation [print-electronic]. 2014 Jan; 85(1): 99-103. PMID: 24036406, PMCID: PMC3905108, PII: S0300-9572(13)00714-4, DOI: 10.1016/j.resuscitation.2013.08.275, ISSN: 1873-1570.

Hollenbeck RD, McPherson JA, Mooney MR, Unger BT, Patel NC, McMullan PW, Hsu CH, Seder DB, Kern KB. Early cardiac catheterization is associated with improved survival in comatose survivors of cardiac arrest without STEMI. Resuscitation [print-electronic]. 2014 Jan; 85(1): 88-95. PMID: 23927955, PII: S0300-9572(13)00396-1, DOI: 10.1016/j.resuscitation.2013.07.027, ISSN: 1873-1570.

McPherson JA, Davis K, Yau M, Beineke P, Rosenberg S, Monane M, Fredi JL. The clinical utility of gene expression testing on the diagnostic evaluation of patients presenting to the cardiologist with symptoms of suspected obstructive coronary artery disease: results from the IMPACT (Investigation of a Molecular Personalized Coronary Gene Expression Test on Cardiology Practice Pattern) trial. Crit Pathw Cardiol. 2013 Jun; 12(2): 37-42. PMID: 23680805, PII: 00132577-201306000-00001, DOI: 10.1097/HPC.0b013e3182822bd0, ISSN: 1535-2811.

McPherson JA, Boehm LM, Wagner C, Ely EW, Pandharipande PP. The authors reply [letter]. Crit. Care Med. 2013 Jun; 41(6): e101-2. PMID: 23685594, PII: 00003246-201306000-00054, DOI: 10.1097/CCM.0b013e31828e8d95, ISSN: 1530-0293.

Thomas GS, Voros S, McPherson JA, Lansky AJ, Winn ME, Bateman TM, Elashoff MR, Lieu HD, Johnson AM, Daniels SE, Ladapo JA, Phelps CE, Douglas PS, Rosenberg S. A blood-based gene expression test for obstructive coronary artery disease tested in symptomatic nondiabetic patients referred for myocardial perfusion imaging the COMPASS study. Circ Cardiovasc Genet [print-electronic]. 2013 Apr; 6(2): 154-62. PMID: 23418288, PII: CIRCGENETICS.112.964015, DOI: 10.1161/CIRCGENETICS.112.964015, ISSN: 1942-3268.

McPherson JA, Wagner CE, Boehm LM, Hall JD, Johnson DC, Miller LR, Burns KM, Thompson JL, Shintani AK, Ely EW, Pandharipande PP. Delirium in the cardiovascular ICU: exploring modifiable risk factors. Crit. Care Med. 2013 Feb; 41(2): 405-13. PMID: 23263581, PMCID: PMC3557701, DOI: 10.1097/CCM.0b013e31826ab49b, ISSN: 1530-0293.

Collins SP, Lindsell CJ, Jenkins CA, Harrell FE, Fermann GJ, Miller KF, Roll SN, Sperling MI, Maron DJ, Naftilan AJ, McPherson JA, Weintraub NL, Sawyer DB, Storrow AB. Risk stratification in acute heart failure: rationale and design of the STRATIFY and DECIDE studies. Am. Heart J [print-electronic]. 2012 Dec; 164(6): 825-34. PMID: 23194482, PMCID: PMC3511776, PII: S0002-8703(12)00663-1, DOI: 10.1016/j.ahj.2012.07.033, ISSN: 1097-6744.

Janz DR, Hollenbeck RD, Pollock JS, McPherson JA, Rice TW. Hyperoxia is associated with increased mortality in patients treated with mild therapeutic hypothermia after sudden cardiac arrest. Crit. Care Med. 2012 Dec; 40(12): 3135-9. PMID: 22971589, PMCID: PMC3502652, DOI: 10.1097/CCM.0b013e3182656976, ISSN: 1530-0293.

Fermann GJ, Lindsell CJ, Storrow AB, Hart K, Sperling M, Roll S, Weintraub NL, Miller KF, Maron DJ, Naftilan AJ, McPherson JA, Sawyer DB, Christenson R, Collins SP. Galectin 3 complements BNP in risk stratification in acute heart failure. Biomarkers [print-electronic]. 2012 Dec; 17(8): 706-13. PMID: 22998064, PMCID: PMC3678263, DOI: 10.3109/1354750X.2012.719037, ISSN: 1366-5804.

Collins SP, Lindsell CJ, Yealy DM, Maron DJ, Naftilan AJ, McPherson JA, Storrow AB. A comparison of criterion standard methods to diagnose acute heart failure. Congest Heart Fail [print-electronic]. 2012 Sep; 18(5): 262-71. PMID: 22994440, PMCID: PMC3458712, DOI: 10.1111/j.1751-7133.2012.00288.x, ISSN: 1751-7133.

Hollenbeck RD, Wells Q, Pollock J, Kelley MB, Wagner CE, Cash ME, Scott C, Burns K, Jones I, Fredi JL, McPherson JA. Implementation of a standardized pathway for the treatment of cardiac arrest patients using therapeutic hypothermia: "CODE ICE". Crit Pathw Cardiol. 2012 Sep; 11(3): 91-8. PMID: 22825528, PII: 00132577-201209000-00001, DOI: 10.1097/HPC.0b013e31825b7bc3, ISSN: 1535-2811.

Xu Y, Mintz GS, Tam A, McPherson JA, Iñiguez A, Fajadet J, Fahy M, Weisz G, De Bruyne B, Serruys PW, Stone GW, Maehara A. Prevalence, distribution, predictors, and outcomes of patients with calcified nodules in native coronary arteries: a 3-vessel intravascular ultrasound analysis from Providing Regional Observations to Study Predictors of Events in the Coronary Tree (PROSPECT). Circulation [print-electronic]. 2012 Jul 7/31/2012; 126(5): 537-45. PMID: 22744975, PII: CIRCULATIONAHA.111.055004, DOI: 10.1161/CIRCULATIONAHA.111.055004, ISSN: 1524-4539.

Pulley JM, Denny JC, Peterson JF, Bernard GR, Vnencak-Jones CL, Ramirez AH, Delaney JT, Bowton E, Brothers K, Johnson K, Crawford DC, Schildcrout J, Masys DR, Dilks HH, Wilke RA, Clayton EW, Shultz E, Laposata M, McPherson J, Jirjis JN, Roden DM. Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project. Clin. Pharmacol. Ther [print-electronic]. 2012 Jul; 92(1): 87-95. PMID: 22588608, PMCID: PMC3581305, PII: clpt2011371, DOI: 10.1038/clpt.2011.371, ISSN: 1532-6535.

Dresen WF, Wells QS, Maron DJ, McPherson JA. Therapeutic procedures for coronary vasospasm-induced polymorphic ventricular tachycardia. Ther Adv Cardiovasc Dis [print-electronic]. 2012 Jun; 6(3): 115-21. PMID: 22547691, PII: 1753944712446303, DOI: 10.1177/1753944712446303, ISSN: 1753-9455.

Rosenberg S, Elashoff MR, Lieu HD, Brown BO, Kraus WE, Schwartz RS, Voros S, Ellis SG, Waksman R, McPherson JA, Lansky AJ, Topol EJ, . Whole blood gene expression testing for coronary artery disease in nondiabetic patients: major adverse cardiovascular events and interventions in the PREDICT trial. J Cardiovasc Transl Res [print-electronic]. 2012 Jun; 5(3): 366-74. PMID: 22396313, PMCID: PMC3349850, DOI: 10.1007/s12265-012-9353-z, ISSN: 1937-5395.

Henry-Okafor Q, Collins SP, Jenkins CA, Miller KF, Maron DJ, Naftilan AJ, Weintraub N, Fermann GJ, McPherson J, Menon S, Sawyer DB, Storrow AB. Soluble ST2 as a Diagnostic and Prognostic Marker for Acute Heart Failure Syndromes. Open Biomark J. 2012 Apr 4/20/2012; 2012(5): 1-8. PMID: 23439880, PMCID: PMC3578210, DOI: 10.2174/1875318301205010001, ISSN: 1875-3183.

McPherson JA, Maehara A, Weisz G, Mintz GS, Cristea E, Mehran R, Foster M, Verheye S, Rabbani L, Xu K, Fahy M, Templin B, Zhang Z, Lansky AJ, de Bruyne B, Serruys PW, Stone GW. Residual plaque burden in patients with acute coronary syndromes after successful percutaneous coronary intervention. JACC Cardiovasc Imaging. 2012 Mar; 5(3 Suppl): S76-85. PMID: 22421234, PII: S1936-878X(12)00050-2, DOI: 10.1016/j.jcmg.2012.01.005, ISSN: 1876-7591.

Brener SJ, Mintz GS, Cristea E, Weisz G, Maehara A, McPherson JA, Marso SP, Farhat N, Botker HE, Dressler O, Xu K, Templin B, Zhang Z, Lansky AJ, de Bruyne B, Serruys PW, Stone GW. Characteristics and clinical significance of angiographically mild lesions in acute coronary syndromes. JACC Cardiovasc Imaging. 2012 Mar; 5(3 Suppl): S86-94. PMID: 22421235, PII: S1936-878X(12)00007-1, DOI: 10.1016/j.jcmg.2011.12.007, ISSN: 1876-7591.

Yu SS, Ortega RA, Reagan BW, McPherson JA, Sung HJ, Giorgio TD. Emerging applications of nanotechnology for the diagnosis and management of vulnerable atherosclerotic plaques. Wiley Interdiscip Rev Nanomed Nanobiotechnol [print-electronic]. 2011 Nov; 3(6): 620-46. PMID: 21834059, DOI: 10.1002/wnan.158, ISSN: 1939-0041.

Fong PP, Jackson EB, Churchwell KB, Steaban R, Starmer JM, Johnson DC, McNeil JD, Klint ZW, Scalf SL, Parsons CM, Cortez S, Christensen D, French T, McPherson JA. Acute coronary syndrome pathways: alignment with a bundled care reimbursement model. Crit Pathw Cardiol. 2011 Mar; 10(1): 1-8. PMID: 21562368, PII: 00132577-201103000-00001, DOI: 10.1097/HPC.0b013e318211bb08, ISSN: 1535-2811.

Wagner C, Fredi J, Bick J, McPherson J. Monitoring myocardial recovery during induced hypothermia with a disposable monoplane TEE probe. Resuscitation [print-electronic]. 2011 Mar; 82(3): 355-7. PMID: 21177014, PII: S0300-9572(10)01073-7, DOI: 10.1016/j.resuscitation.2010.10.031, ISSN: 1873-1570.

Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, Mehran R, McPherson J, Farhat N, Marso SP, Parise H, Templin B, White R, Zhang Z, Serruys PW. A Prospective Natural History Study of Coronary Atherosclerosis. 2011.

Wang G, Zhang S, Joggerst SJ, McPherson J, Zhao DX. Effects of the number and interval of balloon inflations during primary PCI on the extent of myocardial injury in patients with STEMI: does postconditioning exist in real-world practice?. J Invasive Cardiol. 2009 Sep; 21(9): 451-5. PMID: 19726816, ISSN: 1557-2501.

Zhao DX, Leacche M, Balaguer JM, Boudoulas KD, Damp JA, Greelish JP, Byrne JG, , Ahmad RM, Ball SK, Cleator JH, Deegan RJ, Eagle SS, Fong PP, Fredi JL, Hoff SJ, Jennings HS, McPherson JA, Piana RN, Pretorius M, Robbins MA, Slosky DA, Thompson A. Routine intraoperative completion angiography after coronary artery bypass grafting and 1-stop hybrid revascularization results from a fully integrated hybrid catheterization laboratory/operating room. J. Am. Coll. Cardiol. 2009 Jan 1/20/2009; 53(3): 232-41. PMID: 19147039, PII: S0735-1097(08)03463-3, DOI: 10.1016/j.jacc.2008.10.011, ISSN: 1558-3597.