John Robert Koethe, M.D.

Assistant Professor
Faculty Appointments
Assistant Professor of Medicine
M.S.C.I., Clinical Investigation , Vanderbilt University, Nashville, TennesseeM.D., Yale University, New Haven, ConnecticutB.A., Oberlin College, Oberlin, Ohio
Office Address
1161 21st Avenue South
Nashville, TN 37232-2582
Clinical Research Keywords
HIV, obesity, nutrition, inflammation, immunology
Koethe JR, Blevins M, Bosire C, Nyirenda C, Kabagambe EK, Mwango A, Kasongo W, Zulu I, Shepherd BE, Heimburger DC. Self-reported dietary intake and appetite predict early treatment outcome among low-BMI adults initiating HIV treatment in sub-Saharan Africa. Public Health Nutr [print-electronic]. 2013 Mar; 16(3): 549-58. PMID: 22691872, PMCID: PMC3772135, PII: S1368980012002960, DOI: 10.1017/S1368980012002960, ISSN: 1475-2727.

Menge TJ, Koethe JR, Jenkins CA, Wright PW, Shinar AA, Miller GG, Holt GE. Acute kidney injury after placement of an antibiotic-impregnated cement spacer during revision total knee arthroplasty. J Arthroplasty [print-electronic]. 2012 Jun; 27(6): 1221-7.e1. PMID: 22321301, PII: S0883-5403(11)00683-8, DOI: 10.1016/j.arth.2011.12.005, ISSN: 1532-8406.

Koethe JR, Bian A, Shintani AK, Boger MS, Mitchell VJ, Erdem H, Hulgan T. Serum leptin level mediates the association of body composition and serum C-reactive protein in HIV-infected persons on antiretroviral therapy. AIDS Res. Hum. Retroviruses [print-electronic]. 2012 Jun; 28(6): 552-7. PMID: 22145933, PMCID: PMC3358098, DOI: 10.1089/AID.2011.0232, ISSN: 1931-8405.

Koethe JR, Jenkins CA, Shepherd BE, Stinnette SE, Sterling TR. An optimal body mass index range associated with improved immune reconstitution among HIV-infected adults initiating antiretroviral therapy. Clin. Infect. Dis [print-electronic]. 2011 Nov; 53(9): 952-60. PMID: 21946189, PMCID: PMC3189168, PII: cir606, DOI: 10.1093/cid/cir606, ISSN: 1537-6591.

Wester CW, Koethe JR, Shepherd BE, Stinnette SE, Rebeiro PF, Kipp AM, Hong H, Bussmann H, Gaolathe T, McGowan CC, Sterling TR, Marlink RG. Non-AIDS-defining events among HIV-1-infected adults receiving combination antiretroviral therapy in resource-replete versus resource-limited urban setting. AIDS. 2011 Jul 7/31/2011; 25(12): 1471-9. PMID: 21572309, PMCID: PMC3188442, DOI: 10.1097/QAD.0b013e328347f9d4, ISSN: 1473-5571.

Koethe JR, Blevins M, Nyirenda C, Kabagambe EK, Shepherd BE, Wester CW, Zulu I, Chiasera JM, Mulenga LB, Mwango A, Heimburger DC. Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia. J Int AIDS Soc. 2011; 14: 19. PMID: 21477359, PMCID: PMC3094357, PII: 1758-2652-14-19, DOI: 10.1186/1758-2652-14-19, ISSN: 1758-2652.

Koethe JR, Limbada MI, Giganti MJ, Nyirenda CK, Mulenga L, Wester CW, Chi BH, Stringer JS. Early immunologic response and subsequent survival among malnourished adults receiving antiretroviral therapy in Urban Zambia. AIDS. 2010 Aug 8/24/2010; 24(13): 2117-21. PMID: 20543657, PMCID: PMC2919155, DOI: 10.1097/QAD.0b013e32833b784a, ISSN: 1473-5571.

Koethe JR, Heimburger DC. Nutritional aspects of HIV-associated wasting in sub-Saharan Africa. Am. J. Clin. Nutr [print-electronic]. 2010 Apr; 91(4): 1138S-1142S. PMID: 20147470, PMCID: PMC2844686, PII: ajcn.2010.28608D, DOI: 10.3945/ajcn.2010.28608D, ISSN: 1938-3207.

Koethe JR, Lukusa A, Giganti MJ, Chi BH, Nyirenda CK, Limbada MI, Banda Y, Stringer JS. Association between weight gain and clinical outcomes among malnourished adults initiating antiretroviral therapy in Lusaka, Zambia. J. Acquir. Immune Defic. Syndr. 2010 Apr 4/1/2010; 53(4): 507-13. PMID: 19730111, PMCID: PMC3749827, DOI: 10.1097/QAI.0b013e3181b32baf, ISSN: 1944-7884.

Heimburger DC, Koethe JR, Nyirenda C, Bosire C, Chiasera JM, Blevins M, Munoz AJ, Shepherd BE, Potter D, Zulu I, Chisembele-Taylor A, Chi BH, Stringer JS, Kabagambe EK. Serum phosphate predicts early mortality in adults starting antiretroviral therapy in Lusaka, Zambia: a prospective cohort study. PLoS ONE. 2010; 5(5): e10687. PMID: 20502700, PMCID: PMC2872675, DOI: 10.1371/journal.pone.0010687, ISSN: 1932-6203.

Koethe JR, Westfall AO, Luhanga DK, Clark GM, Goldman JD, Mulenga PL, Cantrell RA, Chi BH, Zulu I, Saag MS, Stringer JS. A cluster randomized trial of routine HIV-1 viral load monitoring in Zambia: study design, implementation, and baseline cohort characteristics. PLoS ONE. 2010; 5(3): e9680. PMID: 20300631, PMCID: PMC2837376, DOI: 10.1371/journal.pone.0009680, ISSN: 1932-6203.

Koethe JR, Chi BH, Megazzini KM, Heimburger DC, Stringer JS. Macronutrient supplementation for malnourished HIV-infected adults: a review of the evidence in resource-adequate and resource-constrained settings. Clin. Infect. Dis. 2009 Sep 9/1/2009; 49(5): 787-98. PMID: 19624276, PMCID: PMC3092426, DOI: 10.1086/605285, ISSN: 1537-6591.

Koethe JR, Moore RD, Wagner KR. Physician specialization and women's primary care services in an urban HIV clinic. AIDS Patient Care STDS. 2008 May; 22(5): 373-80. PMID: 18373414, PMCID: PMC2597508, DOI: 10.1089/apc.2007.0032, ISSN: 1557-7449.

Koethe JR, Chang AY. Dyspnea and hemoptysis in a 53-year-old woman with a history of breast cancer. Chest. 2008 May; 133(5): 1248-51. PMID: 18460525, PII: 133/5/1248, DOI: 10.1378/chest.07-2188, ISSN: 0012-3692.