Adetola Kassim, M.B.B.S.

Associate Professor
Faculty Appointments
Associate Professor of Medicine
M.S., Clinical Science Research, Albert Einstein College of Medicine, Yeshiva University, Bronx, New YorkM.B.B.S., Medicine, University of Lagos, Lagos, Nigeria
Office Address
2665 TVC
1301 22nd Avenue South
1301 22nd Avenue South,
Nashville, TN 37232-5505
Research Description
Incidence of pulmonary hypertension in adult sickle cell patients. A prospective case-controlled study.

Research Keywords
stem cell transplant, hematologic malignancies, non-malignant blood disorders, sickle cell
Kassim AA, Galadanci NA, Pruthi S, DeBaun MR. How I treat and manage strokes in sickle cell disease. Blood [print-electronic]. 2015 May 5/28/2015; 125(22): 3401-10. PMID: 25824688, PMCID: PMC4467906, PII: blood-2014-09-551564, DOI: 10.1182/blood-2014-09-551564, ISSN: 1528-0020.

Wolf RB, Saville BR, Roberts DO, Fissell RB, Kassim AA, Airewele G, DeBaun MR. Factors associated with growth and blood pressure patterns in children with sickle cell anemia: Silent Cerebral Infarct Multi-Center Clinical Trial cohort. Am. J. Hematol [print-electronic]. 2015 Jan; 90(1): 2-7. PMID: 25236783, DOI: 10.1002/ajh.23854, ISSN: 1096-8652.

Das-Gupta E, Greinix H, Jacobs R, Zhou L, Savani BN, Engelhardt BG, Kassim A, Worel N, Knobler R, Russell N, Jagasia M. Extracorporeal photopheresis as second-line treatment for acute graft-versus-host disease: impact on six-month freedom from treatment failure. Haematologica [print-electronic]. 2014 Nov; 99(11): 1746-52. PMID: 25150260, PMCID: PMC4222474, PII: haematol.2014.108217, DOI: 10.3324/haematol.2014.108217, ISSN: 1592-8721.

Pidala J, Lee SJ, Ahn KW, Spellman S, Wang HL, Aljurf M, Askar M, Dehn J, Fernandez Viña M, Gratwohl A, Gupta V, Hanna R, Horowitz MM, Hurley CK, Inamoto Y, Kassim AA, Nishihori T, Mueller C, Oudshoorn M, Petersdorf EW, Prasad V, Robinson J, Saber W, Schultz KR, Shaw B, Storek J, Wood WA, Woolfrey AE, Anasetti C. Nonpermissive HLA-DPB1 mismatch increases mortality after myeloablative unrelated allogeneic hematopoietic cell transplantation. Blood [print-electronic]. 2014 Oct 10/16/2014; 124(16): 2596-606. PMID: 25161269, PMCID: PMC4199961, PII: blood-2014-05-576041, DOI: 10.1182/blood-2014-05-576041, ISSN: 1528-0020.

Pauff JM, Gonzalez RS, Sajnani KP, Kassim A, Jagasia M. Post-allograft pomalidomide and reversible hepatotoxicity [letter]. Bone Marrow Transplant [print-electronic]. 2014 Oct; 49(10): 1341-2. PMID: 24955783, PII: bmt2014128, DOI: 10.1038/bmt.2014.128, ISSN: 1476-5365.

Wolf RB, Kassim AA, Goodpaster RL, DeBaun MR. Nocturnal enuresis in sickle cell disease. Expert Rev Hematol. 2014 Apr; 7(2): 245-54. PMID: 24617333, DOI: 10.1586/17474086.2014.892412, ISSN: 1747-4094.

Maheshwari S, Kassim A, Yeh RF, Domm J, Calder C, Evans M, Manes B, Bruce K, Brown V, Ho R, Frangoul H, Yang E. Targeted Busulfan therapy with a steady-state concentration of 600-700¿ng/mL in patients with sickle cell disease receiving HLA-identical sibling bone marrow transplant. Bone Marrow Transplant [print-electronic]. 2014 Mar; 49(3): 366-9. PMID: 24317124, PII: bmt2013188, DOI: 10.1038/bmt.2013.188, ISSN: 1476-5365.

Kassim AA, DeBaun MR. The case for and against initiating either hydroxyurea therapy, blood transfusion therapy or hematopoietic stem cell transplant in asymptomatic children with sickle cell disease. Expert Opin Pharmacother [print-electronic]. 2014 Feb; 15(3): 325-36. PMID: 24392871, DOI: 10.1517/14656566.2014.868435, ISSN: 1744-7666.

Sengsayadeth S, Savani BN, Jagasia M, Goodman S, Greer JP, Chen H, Chinratanalab W, Kassim AA, Engelhardt BG. Six-month freedom from treatment failure is an important end point for acute GVHD clinical trials. Bone Marrow Transplant [print-electronic]. 2014 Feb; 49(2): 236-40. PMID: 24096824, PMCID: PMC3946331, PII: bmt2013157, DOI: 10.1038/bmt.2013.157, ISSN: 1476-5365.

Ragon BK, Clifton C, Chen H, Savani BN, Engelhardt BG, Kassim AA, Vaughan LA, Lucid C, Jagasia M. Geographic distance is not associated with inferior outcome when using long-term transplant clinic strategy. Biol. Blood Marrow Transplant [print-electronic]. 2014 Jan; 20(1): 53-7. PMID: 24120525, PII: S1083-8791(13)00450-3, DOI: 10.1016/j.bbmt.2013.10.004, ISSN: 1523-6536.

Vaughan LA, Vu M, Sengsayadeth S, Lucid C, Clifton C, McCarty K, Hagaman D, Domm J, Kassim A, Chinratanalab W, Goodman S, Greer J, Frangoul H, Engelhardt BG, Jagasia M, Savani BN. New allergies after cord blood transplantation. Cytotherapy. 2013 Oct; 15(10): 1259-65. PMID: 23993300, PII: S1465-3249(13)00550-1, DOI: 10.1016/j.jcyt.2013.05.018, ISSN: 1477-2566.

Jagasia M, Greinix H, Robin M, Das-Gupta E, Jacobs R, Savani BN, Engelhardt BG, Kassim A, Worel N, Knobler R, Russell N, Socie G. Extracorporeal photopheresis versus anticytokine therapy as a second-line treatment for steroid-refractory acute GVHD: a multicenter comparative analysis. Biol. Blood Marrow Transplant [print-electronic]. 2013 Jul; 19(7): 1129-33. PMID: 23623892, PII: S1083-8791(13)00186-9, DOI: 10.1016/j.bbmt.2013.04.018, ISSN: 1523-6536.

Kassim AA, DeBaun MR. Sickle cell disease, vasculopathy, and therapeutics. Annu. Rev. Med [print-electronic]. 2013; 64: 451-66. PMID: 23190149, DOI: 10.1146/annurev-med-120611-143127, ISSN: 1545-326X.

Engelhardt BG, Sengsayadeth SM, Jagasia M, Savani BN, Kassim AA, Lu P, Shyr Y, Yoder SM, Rock MT, Crowe JE. Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival. Exp. Hematol [print-electronic]. 2012 Dec; 40(12): 974-982.e1. PMID: 22885125, PMCID: PMC3611587, PII: S0301-472X(12)00343-8, DOI: 10.1016/j.exphem.2012.08.002, ISSN: 1873-2399.

Sengsayadeth SM, Jagasia M, Engelhardt BG, Kassim A, Strickland SA, Goodman S, Lucid C, Vnencak-Jones CL, Greer JP, Savani BN. Allo-SCT for high-risk AML-CR1 in the molecular era: impact of FLT3/ITD outweighs the conventional markers. Bone Marrow Transplant [print-electronic]. 2012 Dec; 47(12): 1535-7. PMID: 22659680, PII: bmt201288, DOI: 10.1038/bmt.2012.88, ISSN: 1476-5365.

Hart AJ, Jagasia MH, Kim AS, Mosse CA, Savani BN, Kassim A. Minimal residual disease in myeloma: are we there yet?. Biol. Blood Marrow Transplant [print-electronic]. 2012 Dec; 18(12): 1790-9. PMID: 22626785, PII: S1083-8791(12)00211-X, DOI: 10.1016/j.bbmt.2012.05.009, ISSN: 1523-6536.

Jacobs R, Tran U, Chen H, Kassim A, Engelhardt BG, Greer JP, Goodman SG, Clifton C, Lucid C, Vaughan LA, Savani BN, Jagasia M. Prevalence and risk factors associated with development of ocular GVHD defined by NIH consensus criteria. Bone Marrow Transplant [print-electronic]. 2012 Nov; 47(11): 1470-3. PMID: 22484321, PII: bmt201256, DOI: 10.1038/bmt.2012.56, ISSN: 1476-5365.

Chinratanalab W, Reddy N, Greer JP, Morgan D, Engelhardt B, Kassim A, Brandt SJ, Jagasia M, Goodman S, Savani BN. Immunomodulatory nonablative conditioning regimen for B-cell lymphoid malignancies. Exp. Hematol [print-electronic]. 2012 Jun; 40(6): 431-5. PMID: 22269114, PMCID: PMC4067702, PII: S0301-472X(12)00016-1, DOI: 10.1016/j.exphem.2012.01.014, ISSN: 1873-2399.

Reddy N, Greer JP, Goodman S, Kassim A, Morgan DS, Chinratanalab W, Brandt S, Englehardt B, Oluwole O, Jagasia MH, Savani BN. Consolidative therapy with stem cell transplantation improves survival of patients with mantle cell lymphoma after any induction regimen. Exp. Hematol [print-electronic]. 2012 May; 40(5): 359-66. PMID: 22269117, PII: S0301-472X(12)00014-8, DOI: 10.1016/j.exphem.2012.01.012, ISSN: 1873-2399.

Engelhardt BG, Jagasia SM, Crowe JE, Griffith ML, Savani BN, Kassim AA, Lu P, Weitkamp JH, Moore DJ, Yoder SM, Rock MT, Jagasia M. Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood [print-electronic]. 2012 Mar 3/8/2012; 119(10): 2417-21. PMID: 22262764, PMCID: PMC3311262, PII: blood-2011-10-384750, DOI: 10.1182/blood-2011-10-384750, ISSN: 1528-0020.

Kassim AA, Umans H, Nagel RL, Fabry ME. Megalophallus as a sequela of priapism in sickle cell anemia: use of blood oxygen level-dependent magnetic resonance imaging. Urology. 2000; 1;56((3)): 509.

Kassim AA, Fabry ME, Nagel RL. Acute priapism associated with the use of sildenafil in a patient with sickle cell trait. (Letter). Blood. 2000; 1;95((5)): 1878-9.

Fabry, M.E., Liu, G., Kassim, A., Billet, H., Nagel, R.L. Deoxy HbS detection in brain of sickle cell disease patients by blood level oxygen dependent magnetic resonance imaging (BOLD-MRI). (Abstract). Blood. 1999; ((94)): 421a.

Fabry, M.E., Kassim, A., Umans, H., Nagel, R.L. Clinical applications of BOLD-MRI to extremities in sickle cell pain episodes. (Abstract). Blood. 1998; ((9, 92)): 525a.

Kassim, A., Sane, P., Billett, H. Tower skill or marrow expansion with pituitary hemosiderosis in beta thalassemia intermedia. Journal of Radiology.