Christianne L. Roumie, M.D.

Associate Professor
Faculty Appointments
Associate Professor of Medicine Associate Professor of Pediatrics
M.P.H., Public Health , Vanderbilt University, Nashville, TennesseeM.D., Medicine, New Jersey Medical School, Newark, New JerseyB.A., Douglass College, New Brunswick, New Jersey
Office Address
1310 24th Ave South
Nashville, TN VAMC
Research Keywords
Epidemiology and Outcomes ersearch
Min JY, Griffin MR, Hung AM, Grijalva CG, Greevy RA, Liu X, Elasy T, Roumie CL. Comparative Effectiveness of Insulin versus Combination Sulfonylurea and Insulin: a Cohort Study of Veterans with Type 2 Diabetes. J Gen Intern Med. 2016 Jun; 31(6): 638-46. PMID: 26921160, PMCID: PMC4870423, PII: 10.1007/s11606-016-3633-2, DOI: 10.1007/s11606-016-3633-2, ISSN: 1525-1497.

Williamson JD, Supiano MA, Applegate WB, Berlowitz DR, Campbell RC, Chertow GM, Fine LJ, Haley WE, Hawfield AT, Ix JH, Kitzman DW, Kostis JB, Krousel-Wood MA, Launer LJ, Oparil S, Rodriguez CJ, Roumie CL, Shorr RI, Sink KM, Wadley VG, Whelton PK, Whittle J, Woolard NF, Wright JT, Pajewski NM, . Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged =75 Years: A Randomized Clinical Trial. JAMA [print-electronic]. 2016 May 5/19/2016; PMID: 27195814, PII: 2524266, DOI: 10.1001/jama.2016.7050, ISSN: 1538-3598.

Pajewski NM, Williamson JD, Applegate WB, Berlowitz DR, Bolin LP, Chertow GM, Krousel-Wood MA, Lopez-Barrera N, Powell JR, Roumie CL, Still C, Sink KM, Tang R, Wright CB, Supiano MA, . Characterizing Frailty Status in the Systolic Blood Pressure Intervention Trial. J. Gerontol. A Biol. Sci. Med. Sci [print-electronic]. 2016 May; 71(5): 649-55. PMID: 26755682, PII: glv228, DOI: 10.1093/gerona/glv228, ISSN: 1758-535X.

Bell SP, Schnipper JL, Goggins K, Bian A, Shintani A, Roumie CL, Dalal AK, Jacobson TA, Rask KJ, Vaccarino V, Gandhi TK, Labonville SA, Johnson D, Neal EB, Kripalani S, . Effect of Pharmacist Counseling Intervention on Health Care Utilization Following Hospital Discharge: A Randomized Control Trial. J Gen Intern Med. 2016 May; 31(5): 470-7. PMID: 26883526, PMCID: PMC4835388, PII: 10.1007/s11606-016-3596-3, DOI: 10.1007/s11606-016-3596-3, ISSN: 1525-1497.

Roumie CL, Min JY, Greevy RA, Grijalva CG, Hung AM, Liu X, Elasy T, Griffin MR. Risk of hypoglycemia following intensification of metformin treatment with insulin versus sulfonylurea. CMAJ [print-electronic]. 2016 Apr 4/5/2016; 188(6): E104-12. PMID: 26811361, PMCID: PMC4818151, PII: cmaj.150904, DOI: 10.1503/cmaj.150904, ISSN: 1488-2329.

Kummerow Broman K, Vella MA, Tarpley JL, Dittus RS, Roumie CL. Identification of postoperative care amenable to telehealth. Surgery [print-electronic]. 2016 Apr 4/5/2016; PMID: 27059636, PII: S0039-6060(16)00089-1, DOI: 10.1016/j.surg.2016.02.015, ISSN: 1532-7361.

Chang TI, Evans G, Cheung AK, Cushman WC, Diamond MJ, Dwyer JP, Huan Y, Kitzman D, Kostis JB, Oparil S, Rastogi A, Roumie CL, Sahay R, Stafford RS, Taylor AA, Wright JT, Chertow GM, . Patterns and Correlates of Baseline Thiazide-Type Diuretic Prescription in the Systolic Blood Pressure Intervention Trial. Hypertension [print-electronic]. 2016 Mar; 67(3): 550-5. PMID: 26865200, PMCID: PMC4755350, PII: HYPERTENSIONAHA.115.06851, DOI: 10.1161/HYPERTENSIONAHA.115.06851, ISSN: 1524-4563.

Roumie CL, Greevy RA, Grijalva CG, Hung AM, Liu X, Griffin MR. Diabetes treatment intensification and associated changes in HbA1c and body mass index: a cohort study. BMC Endocr Disord. 2016; 16(1): 32. PMID: 27255309, PMCID: PMC4890276, PII: 10.1186/s12902-016-0101-2, DOI: 10.1186/s12902-016-0101-2, ISSN: 1472-6823.

Vella MA, Kummerow Broman K, Tarpley JL, Dittus RS, Roumie CL. Postoperative Telehealth Visits: Assessment of Quality and Preferences of Veterans [letter]. JAMA Surg. 2015 Dec; 150(12): 1197-9. PMID: 26398664, PII: 2442534, DOI: 10.1001/jamasurg.2015.2660, ISSN: 2168-6262.

McNaughton CD, Cawthon C, Kripalani S, Liu D, Storrow AB, Roumie CL. Health literacy and mortality: a cohort study of patients hospitalized for acute heart failure. J Am Heart Assoc. 2015 May; 4(5): PMID: 25926328, PMCID: PMC4599411, PII: jah3939, DOI: 10.1161/JAHA.115.001799, ISSN: 2047-9980.

Roumie CL, Zillich AJ, Bravata DM, Jaynes HA, Myers LJ, Yoder J, Cheng EM. Hypertension treatment intensification among stroke survivors with uncontrolled blood pressure. Stroke [print-electronic]. 2015 Feb; 46(2): 465-70. PMID: 25550374, PMCID: PMC4308422, PII: STROKEAHA.114.007566, DOI: 10.1161/STROKEAHA.114.007566, ISSN: 1524-4628.

Grijalva CG, Roumie CL, Murff HJ, Hung AM, Beck C, Liu X, Griffin MR, Greevy RA. The role of matching when adjusting for baseline differences in the outcome variable of comparative effectiveness studies. J Comp Eff Res. 2015; 4(4): 341-9. PMID: 26274795, PMCID: PMC4699664, DOI: 10.2217/cer.15.16, ISSN: 2042-6313.

Murff HJ, Roumie CL, Greevy RA, Grijalva CG, Hung AH, Liu X, Griffin MR. Thiazolidinedione and Metformin Use and the Risk of Benign Prostate Hyperplasia in Veterans with Diabetes Mellitus. J Mens Health. 2014 Dec 12/1/2014; 11(4): 157-62. PMID: 25798210, PMCID: PMC4364420, DOI: 10.1089/jomh.2014.0051, ISSN: 1875-6867.

Roumie CL, Greevy RA, Griffin MR. Insulin vs sulfonylureas for second-line diabetes treatment [letter]. JAMA. 2014 Oct 10/22/2014; 312(16): 1694. PMID: 25335156, PII: 1917425, DOI: 10.1001/jama.2014.11126, ISSN: 1538-3598.

Roumie CL, Greevy RA, Griffin MR. Insulin vs sulfonylureas for second-line diabetes treatment--reply [letter]. JAMA. 2014 Oct 10/22/2014; 312(16): 1693-4. PMID: 25335155, PII: 1917427, DOI: 10.1001/jama.2014.11120, ISSN: 1538-3598.

Snyder RA, Mainthia R, Patel R, Dittus RS, Roumie CL. Quality of colorectal cancer care among veterans: a 10-year retrospective cohort. Ann. Surg. Oncol [print-electronic]. 2014 Aug; 21(8): 2476-83. PMID: 24748162, DOI: 10.1245/s10434-014-3689-3, ISSN: 1534-4681.

Roumie CL, Greevy RA, Grijalva CG, Hung AM, Liu X, Murff HJ, Elasy TA, Griffin MR. Association between intensification of metformin treatment with insulin vs sulfonylureas and cardiovascular events and all-cause mortality among patients with diabetes. JAMA. 2014 Jun 6/11/2014; 311(22): 2288-96. PMID: 24915260, PMCID: PMC4149288, PII: 1878717, DOI: 10.1001/jama.2014.4312, ISSN: 1538-3598.

Hung AM, Roumie CL. Blood pressure goals: how low is safe in CKD? [editorial]. Am. J. Kidney Dis [print-electronic]. 2014 Jun; 63(6): 892-4. PMID: 24679896, PII: S0272-6386(14)00591-5, DOI: 10.1053/j.ajkd.2014.02.011, ISSN: 1523-6838.

Karpinos AR, Rizzone KH, Cribbs SP, Roumie CL. Low proportion of high school senior athletes receiving recommended immunizations. Phys Sportsmed. 2014 May; 42(2): 71-9. PMID: 24875974, DOI: 10.3810/psm.2014.05.2059, ISSN: 0091-3847.

McNaughton CD, Kripalani S, Cawthon C, Mion LC, Wallston KA, Roumie CL. Association of health literacy with elevated blood pressure: a cohort study of hospitalized patients. Med Care. 2014 Apr; 52(4): 346-53. PMID: 24556896, PMCID: PMC4031281, DOI: 10.1097/MLR.0000000000000101, ISSN: 1537-1948.

Cawthon C, Mion LC, Willens DE, Roumie CL, Kripalani S. Implementing routine health literacy assessment in hospital and primary care patients. Jt Comm J Qual Patient Saf. 2014 Feb; 40(2): 68-76. PMID: 24716329, PMCID: PMC4072202, ISSN: 1553-7250.

Schmittdiel JA, Adams SR, Segal J, Griffin MR, Roumie CL, Ohnsorg K, Grant RW, O'Connor PJ. Novel use and utility of integrated electronic health records to assess rates of prediabetes recognition and treatment: brief report from an integrated electronic health records pilot study. Diabetes Care [print-electronic]. 2014 Feb; 37(2): 565-8. PMID: 24271190, PMCID: PMC3898765, PII: dc13-1223, DOI: 10.2337/dc13-1223, ISSN: 1935-5548.

Karpinos AR, Roumie CL, Nian H, Diamond AB, Rothman RL. High prevalence of hypertension among collegiate football athletes. Circ Cardiovasc Qual Outcomes [print-electronic]. 2013 Nov; 6(6): 716-23. PMID: 24221829, PMCID: PMC3975920, PII: CIRCOUTCOMES.113.000463, DOI: 10.1161/CIRCOUTCOMES.113.000463, ISSN: 1941-7705.

Bowen ME, Bosworth HB, Roumie CL. Blood pressure control in a hypertension telemedicine intervention: does distance to primary care matter?. J Clin Hypertens (Greenwich) [print-electronic]. 2013 Oct; 15(10): 723-30. PMID: 24088280, DOI: 10.1111/jch.12172, ISSN: 1751-7176.

Hung AM, Roumie CL, Greevy RA, Liu X, Grijalva CG, Murff HJ, Griffin MR. Kidney function decline in metformin versus sulfonylurea initiators: assessment of time-dependent contribution of weight, blood pressure, and glycemic control. Pharmacoepidemiol Drug Saf. 2013 Jun; 22(6): 623-31. PMID: 23592561, DOI: 10.1002/pds.3432, ISSN: 1099-1557.

Niesner K, Murff HJ, Griffin MR, Wasserman B, Greevy R, Grijalva CG, Roumie CL. Validation of VA administrative data algorithms for identifying cardiovascular disease hospitalization [letter]. Epidemiology. 2013 Mar; 24(2): 334-5. PMID: 23377095, PMCID: PMC4667547, PII: 00001648-201303000-00025, DOI: 10.1097/EDE.0b013e3182821e75, ISSN: 1531-5487.

Ikard RW, Snyder RA, Roumie CL. Postoperative morbidity and mortality among Veterans Health Administration patients undergoing surgical resection for large bowel polyps (bowel resection for polyps). Dig Surg [print-electronic]. 2013; 30(4-6): 394-400. PMID: 24192456, PII: 000355647, DOI: 10.1159/000355647, ISSN: 1421-9883.

Willens DE, Kripalani S, Schildcrout JS, Cawthon C, Wallston K, Mion LC, Davis C, Danciu I, Rothman RL, Roumie CL. Association of brief health literacy screening and blood pressure in primary care. J Health Commun. 2013; 18 Suppl 1: 129-42. PMID: 24093351, PMCID: PMC3815081, DOI: 10.1080/10810730.2013.825663, ISSN: 1087-0415.

Shaw RJ, Kaufman MA, Bosworth HB, Weiner BJ, Zullig LL, Lee SY, Kravetz JD, Rakley SM, Roumie CL, Bowen ME, Del Monte PS, Oddone EZ, Jackson GL. Organizational factors associated with readiness to implement and translate a primary care based telemedicine behavioral program to improve blood pressure control: the HTN-IMPROVE study. Implement Sci. 2013; 8: 106. PMID: 24010683, PMCID: PMC3847033, PII: 1748-5908-8-106, DOI: 10.1186/1748-5908-8-106, ISSN: 1748-5908.

Roumie CL, Hung AM, Greevy RA, Grijalva CG, Liu X, Murff HJ, Elasy TA, Griffin MR. Comparative effectiveness of sulfonylurea and metformin monotherapy on cardiovascular events in type 2 diabetes mellitus: a cohort study. Ann. Intern. Med. 2012 Nov 11/6/2012; 157(9): 601-10. PMID: 23128859, PMCID: PMC4667563, PII: 1389845, DOI: 10.7326/0003-4819-157-9-201211060-00003, ISSN: 1539-3704.

Salanitro AH, Osborn CY, Schnipper JL, Roumie CL, Labonville S, Johnson DC, Neal E, Cawthon C, Businger A, Dalal AK, Kripalani S. Erratum to: effect of patient- and medication-related factors on inpatient medication reconciliation errors [letter]. J Gen Intern Med. 2012 Oct; 27(10): 1393. PMID: 22836952, PMCID: PMC3445675, DOI: 10.1007/s11606-012-2149-7, ISSN: 1525-1497.

Salanitro AH, Osborn CY, Schnipper JL, Roumie CL, Labonville S, Johnson DC, Neal E, Cawthon C, Businger A, Dalal AK, Kripalani S. Effect of patient- and medication-related factors on inpatient medication reconciliation errors. J Gen Intern Med [print-electronic]. 2012 Aug; 27(8): 924-32. PMID: 22350761, PMCID: PMC3403136, DOI: 10.1007/s11606-012-2003-y, ISSN: 1525-1497.

Kripalani S, Roumie CL, Dalal AK, Cawthon C, Businger A, Eden SK, Shintani A, Sponsler KC, Harris LJ, Theobald C, Huang RL, Scheurer D, Hunt S, Jacobson TA, Rask KJ, Vaccarino V, Gandhi TK, Bates DW, Williams MV, Schnipper JL, . Effect of a pharmacist intervention on clinically important medication errors after hospital discharge: a randomized trial. Ann. Intern. Med. 2012 Jul 7/3/2012; 157(1): 1-10. PMID: 22751755, PMCID: PMC3575734, PII: 1206684, DOI: 10.7326/0003-4819-157-1-201207030-00003, ISSN: 1539-3704.

Roumie CL. The doughnut hole: it's about medication adherence [editorial]. Ann. Intern. Med. 2012 Jun 6/5/2012; 156(11): 834-5. PMID: 22665817, PII: 156/11/834, DOI: 10.7326/0003-4819-156-11-201206050-00010, ISSN: 1539-3704.

Greevy RA, Grijalva CG, Roumie CL, Beck C, Hung AM, Murff HJ, Liu X, Griffin MR. Reweighted Mahalanobis distance matching for cluster-randomized trials with missing data. Pharmacoepidemiol Drug Saf. 2012 May; 21 Suppl 2: 148-54. PMID: 22552990, PMCID: PMC3760213, DOI: 10.1002/pds.3260, ISSN: 1099-1557.

Roumie CL, Liu X, Choma NN, Greevy RA, Hung AM, Grijalva CG, Griffin MR. Initiation of sulfonylureas versus metformin is associated with higher blood pressure at one year. Pharmacoepidemiol Drug Saf [print-electronic]. 2012 May; 21(5): 515-23. PMID: 22431419, PMCID: PMC4667555, DOI: 10.1002/pds.3249, ISSN: 1099-1557.

Hung AM, Roumie CL, Greevy RA, Liu X, Grijalva CG, Murff HJ, Ikizler TA, Griffin MR. Comparative effectiveness of incident oral antidiabetic drugs on kidney function. Kidney Int [print-electronic]. 2012 Apr; 81(7): 698-706. PMID: 22258320, PMCID: PMC3306005, PII: ki2011444, DOI: 10.1038/ki.2011.444, ISSN: 1523-1755.

Greevy RA, Huizinga MM, Roumie CL, Grijalva CG, Murff H, Liu X, Griffin MR. Comparisons of persistence and durability among three oral antidiabetic therapies using electronic prescription-fill data: the impact of adherence requirements and stockpiling. Clin. Pharmacol. Ther [print-electronic]. 2011 Dec; 90(6): 813-9. PMID: 22048232, PII: clpt2011228, DOI: 10.1038/clpt.2011.228, ISSN: 1532-6535.

Roumie CL, Greevy R, Wallston KA, Elasy TA, Kaltenbach L, Kotter K, Dittus RS, Speroff T. Patient centered primary care is associated with patient hypertension medication adherence. J Behav Med [print-electronic]. 2011 Aug; 34(4): 244-53. PMID: 21161578, DOI: 10.1007/s10865-010-9304-6, ISSN: 1573-3521.

Roumie CL, Ofner S, Ross JS, Arling G, Williams LS, Ordin DL, Bravata DM. Prevalence of inadequate blood pressure control among veterans after acute ischemic stroke hospitalization: a retrospective cohort. Circ Cardiovasc Qual Outcomes [print-electronic]. 2011 Jul; 4(4): 399-407. PMID: 21693725, PMCID: PMC3140571, PII: CIRCOUTCOMES.110.959809, DOI: 10.1161/CIRCOUTCOMES.110.959809, ISSN: 1941-7705.

Roumie CL, Huizinga MM, Liu X, Greevy RA, Grijalva CG, Murff HJ, Hung AM, Griffin MR. The effect of incident antidiabetic regimens on lipid profiles in veterans with type 2 diabetes: a retrospective cohort. Pharmacoepidemiol Drug Saf [print-electronic]. 2011 Jan; 20(1): 36-44. PMID: 21182152, DOI: 10.1002/pds.2029, ISSN: 1099-1557.

Schnipper JL, Roumie CL, Cawthon C, Businger A, Dalal AK, Mugalla I, Eden S, Jacobson TA, Rask KJ, Vaccarino V, Gandhi TK, Bates DW, Johnson DC, Labonville S, Gregory D, Kripalani S, . Rationale and design of the Pharmacist Intervention for Low Literacy in Cardiovascular Disease (PILL-CVD) study. Circ Cardiovasc Qual Outcomes. 2010 Mar; 3(2): 212-9. PMID: 20233982, PMCID: PMC3021350, PII: 3/2/212, DOI: 10.1161/CIRCOUTCOMES.109.921833, ISSN: 1941-7705.

Roumie CL, Choma NN, Kaltenbach L, Mitchel EF, Arbogast PG, Griffin MR. Non-aspirin NSAIDs, cyclooxygenase-2 inhibitors and risk for cardiovascular events-stroke, acute myocardial infarction, and death from coronary heart disease. Pharmacoepidemiol Drug Saf. 2009 Nov; 18(11): 1053-63. PMID: 19637402, DOI: 10.1002/pds.1820, ISSN: 1099-1557.

Roumie CL, Mitchel EF, Kaltenbach L, Arbogast PG, Gideon P, Griffin MR. Nonaspirin NSAIDs, cyclooxygenase 2 inhibitors, and the risk for stroke. Stroke [print-electronic]. 2008 Jul; 39(7): 2037-45. PMID: 18436878, PII: STROKEAHA.107.508549, DOI: 10.1161/STROKEAHA.107.508549, ISSN: 1524-4628.

Roumie CL, Mitchel E, Gideon PS, Varas-Lorenzo C, Castellsague J, Griffin MR. Validation of ICD-9 codes with a high positive predictive value for incident strokes resulting in hospitalization using Medicaid health data. Pharmacoepidemiol Drug Saf. 2008 Jan; 17(1): 20-6. PMID: 17979142, DOI: 10.1002/pds.1518, ISSN: 1053-8569.

Roumie CL, Elasy TA, Wallston KA, Pratt S, Greevy RA, Liu X, Alvarez V, Dittus RS, Speroff T. Clinical inertia: a common barrier to changing provider prescribing behavior. Jt Comm J Qual Patient Saf. 2007 May; 33(5): 277-85. PMID: 17503683, ISSN: 1553-7250.

Roumie CL, Elasy TA, Greevy R, Griffin MR, Liu X, Stone WJ, Wallston KA, Dittus RS, Alvarez V, Cobb J, Speroff T. Improving blood pressure control through provider education, provider alerts, and patient education: a cluster randomized trial. Ann. Intern. Med. 2006 Aug 8/1/2006; 145(3): 165-75. PMID: 16880458, PII: 145/3/165, ISSN: 1539-3704.

Roumie CL, Arbogast PG, Mitchel EF, Griffin MR. Prescriptions for chronic high-dose cyclooxygenase-2 inhibitors are often inappropriate and potentially dangerous. J Gen Intern Med. 2005 Oct; 20(10): 879-83. PMID: 16191131, PMCID: PMC1490217, PII: JGI173, DOI: 10.1111/j.1525-1497.2005.0173.x, ISSN: 1525-1497.

Roumie CL, Halasa NB, Grijalva CG, Edwards KM, Zhu Y, Dittus RS, Griffin MR. Trends in antibiotic prescribing for adults in the United States--1995 to 2002. J Gen Intern Med. 2005 Aug; 20(8): 697-702. PMID: 16050877, PMCID: PMC1490171, PII: JGI05620, DOI: 10.1111/j.1525-1497.2005.0148.x, ISSN: 1525-1497.

Roumie CL, Halasa NB, Edwards KM, Zhu Y, Dittus RS, Griffin MR. Differences in antibiotic prescribing among physicians, residents, and nonphysician clinicians. Am. J. Med. 2005 Jun; 118(6): 641-8. PMID: 15922696, PII: S0002-9343(05)00099-9, DOI: 10.1016/j.amjmed.2005.02.013, ISSN: 0002-9343.

Grogan EL, Speroff T, Deppen SA, Roumie CL, Elasy TA, Dittus RS, Rosenbloom ST, Holzman MD. Improving documentation of patient acuity level using a progress note template. J. Am. Coll. Surg. 2004 Sep; 199(3): 468-75. PMID: 15325618, PII: S1072-7515(04)00702-1, DOI: 10.1016/j.jamcollsurg.2004.05.254, ISSN: 1072-7515.

Roumie CL, Grogan EL, Falbe W, Awad J, Speroff T, Dittus RS, Elasy TA. A three-part intervention to change the use of hormone replacement therapy in response to new evidence. Ann. Intern. Med. 2004 Jul 7/20/2004; 141(2): 118-25. PMID: 15262667, PII: 141/2/118, ISSN: 1539-3704.

Roumie CL, Griffin MR. Over-the-counter analgesics in older adults: a call for improved labelling and consumer education. Drugs Aging. 2004; 21(8): 485-98. PMID: 15182214, PII: 2181, ISSN: 1170-229X.