Mary Kay Washington, Ph.D., M.D.

Faculty Appointments
Professor of Pathology, Microbiology and Immunology
M.D., University of North Carolina School of Medicine, Chapel Hill, North CarolinaPh.D., Physical Chemistry, University of North Carolina, Chapel Hill, North CarolinaB.S., Chemistry, Mississippi State University, Starkville, Mississippi
Office Address
C-3321 MCN
1161 21st Ave South
Nashville, TN 37232-2561
Research Description
My research focuses on morphology of gastrointestinal and hepatic diseases. I provide expertise in interpretation of histopathologic changes in a variety of animal models of gastrointestinal diseases to basic scientists at Vanderbilt. I also serve as Director for several research biorepositories and shared resources, including the Vanderbilt Digestive Diseases Research Center and the Western Division of the Cooperative Human Tissue Network.

Research Keywords
Histopathology of gastrointestinal and hepatic diseases and mouse models of GI cancer
Clinical Research Keywords
diagnostic gastrointestinal and hepatic pathology; immunohistochemistry
Peng D, Belkhiri A, Hu T, Chaturvedi R, Asim M, Wilson KT, Zaika A, El-Rifai W. Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells. Gut [print-electronic]. 2012 Sep; 61(9): 1250-60. PMID: 22157330, PMCID: PMC3419307, PII: gutjnl-2011-301078, DOI: 10.1136/gutjnl-2011-301078, ISSN: 1468-3288.

Zhang Y, Dubé PE, Washington MK, Yan F, Polk DB. ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival. Lab. Invest [print-electronic]. 2012 Mar; 92(3): 437-50. PMID: 22157714, PMCID: PMC3289719, PII: labinvest2011192, DOI: 10.1038/labinvest.2011.192, ISSN: 1530-0307.

Freeman TJ, Smith JJ, Chen X, Washington MK, Roland JT, Means AL, Eschrich SA, Yeatman TJ, Deane NG, Beauchamp RD. Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of ß-catenin. Gastroenterology [print-electronic]. 2012 Mar; 142(3): 562-571.e2. PMID: 22115830, PMCID: PMC3343368, PII: S0016-5085(11)01622-2, DOI: 10.1053/j.gastro.2011.11.026, ISSN: 1528-0012.

Singh AB, Sharma A, Smith JJ, Krishnan M, Chen X, Eschrich S, Washington MK, Yeatman TJ, Beauchamp RD, Dhawan P. Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells. Gastroenterology [print-electronic]. 2011 Dec; 141(6): 2140-53. PMID: 21878201, PMCID: PMC3395068, PII: S0016-5085(11)01221-2, DOI: 10.1053/j.gastro.2011.08.038, ISSN: 1528-0012.

Rosen MJ, Frey MR, Washington MK, Chaturvedi R, Kuhnhein LA, Matta P, Revetta FL, Wilson KT, Polk DB. STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction. Inflamm. Bowel Dis [print-electronic]. 2011 Nov; 17(11): 2224-34. PMID: 21308881, PMCID: PMC3120916, DOI: 10.1002/ibd.21628, ISSN: 1536-4844.

Williams CS, Zhang B, Smith JJ, Jayagopal A, Barrett CW, Pino C, Russ P, Presley SH, Peng D, Rosenblatt DO, Haselton FR, Yang JL, Washington MK, Chen X, Eschrich S, Yeatman TJ, El-Rifai W, Beauchamp RD, Chang MS. BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma. J. Clin. Invest [print-electronic]. 2011 Oct; 121(10): 4056-69. PMID: 21911938, PMCID: PMC3195453, PII: 44228, DOI: 10.1172/JCI44228, ISSN: 1558-8238.

Ueda Y, Hajri T, Peng D, Marks-Shulman PA, Tamboli RA, Shukrallah B, Saliba J, Jabbour K, El-Rifai W, Abumrad NA, Abumrad NN. Reduction of 8-iso-prostaglandin F2a in the first week after Roux-en-Y gastric bypass surgery. Obesity (Silver Spring) [print-electronic]. 2011 Aug; 19(8): 1663-8. PMID: 21475145, PMCID: PMC3176330, PII: oby201158, DOI: 10.1038/oby.2011.58, ISSN: 1930-739X.

Dhawan P, Ahmad R, Chaturvedi R, Smith JJ, Midha R, Mittal MK, Krishnan M, Chen X, Eschrich S, Yeatman TJ, Harris RC, Washington MK, Wilson KT, Beauchamp RD, Singh AB. Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation. Oncogene [print-electronic]. 2011 Jul 7/21/2011; 30(29): 3234-47. PMID: 21383692, PMCID: PMC3591522, PII: onc201143, DOI: 10.1038/onc.2011.43, ISSN: 1476-5594.

Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB. Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. J. Clin. Invest [print-electronic]. 2011 Jun; 121(6): 2242-53. PMID: 21606592, PMCID: PMC3104743, PII: 44031, DOI: 10.1172/JCI44031, ISSN: 1558-8238.

Soutto M, Belkhiri A, Piazuelo MB, Schneider BG, Peng D, Jiang A, Washington MK, Kokoye Y, Crowe SE, Zaika A, Correa P, Peek RM, El-Rifai W. Loss of TFF1 is associated with activation of NF-¿B-mediated inflammation and gastric neoplasia in mice and humans. J. Clin. Invest [print-electronic]. 2011 May; 121(5): 1753-67. PMID: 21490402, PMCID: PMC3083788, PII: 43922, DOI: 10.1172/JCI43922, ISSN: 1558-8238.

Barrett CW, Fingleton B, Williams A, Ning W, Fischer MA, Washington MK, Chaturvedi R, Wilson KT, Hiebert SW, Williams CS. MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model. Cancer Res [print-electronic]. 2011 Feb 2/15/2011; 71(4): 1302-12. PMID: 21303973, PMCID: PMC3150168, PII: 0008-5472.CAN-10-3317, DOI: 10.1158/0008-5472.CAN-10-3317, ISSN: 1538-7445.

Singh K, Chaturvedi R, Barry DP, Coburn LA, Asim M, Lewis ND, Piazuelo MB, Washington MK, Vitek MP, Wilson KT. The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. J. Biol. Chem [print-electronic]. 2011 Feb 2/4/2011; 286(5): 3839-50. PMID: 21115487, PMCID: PMC3030385, PII: M110.176719, DOI: 10.1074/jbc.M110.176719, ISSN: 1083-351X.

Nagaraj NS, Washington MK, Merchant NB. Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth. Clin. Cancer Res [print-electronic]. 2011 Feb 2/1/2011; 17(3): 483-93. PMID: 21266529, PMCID: PMC3079196, PII: 1078-0432.CCR-10-1670, DOI: 10.1158/1078-0432.CCR-10-1670, ISSN: 1078-0432.

Goettel JA, Scott Algood HM, Olivares-Villagómez D, Washington MK, Chaturvedi R, Wilson KT, Van Kaer L, Polk DB. KSR1 protects from interleukin-10 deficiency-induced colitis in mice by suppressing T-lymphocyte interferon-¿ production. Gastroenterology [print-electronic]. 2011 Jan; 140(1): 265-74. PMID: 20875416, PMCID: PMC3008308, PII: S0016-5085(10)01421-6, DOI: 10.1053/j.gastro.2010.09.041, ISSN: 1528-0012.

Le Bras GF, Allison GL, Richards NF, Ansari SS, Washington MK, Andl CD. CD44 upregulation in E-cadherin-negative esophageal cancers results in cell invasion. PLoS ONE [print-electronic]. 2011; 6(11): e27063. PMID: 22069487, PMCID: PMC3206075, PII: PONE-D-11-14715, DOI: 10.1371/journal.pone.0027063, ISSN: 1932-6203.

Peng D, Hu TL, Jiang A, Washington MK, Moskaluk CA, Schneider-Stock R, El-Rifai W. Location-specific epigenetic regulation of the metallothionein 3 gene in esophageal adenocarcinomas. PLoS ONE [print-electronic]. 2011; 6(7): e22009. PMID: 21818286, PMCID: PMC3139601, PII: PONE-D-11-06954, DOI: 10.1371/journal.pone.0022009, ISSN: 1932-6203.

Smalley-Freed WG, Efimov A, Short SP, Jia P, Zhao Z, Washington MK, Robine S, Coffey RJ, Reynolds AB. Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS ONE [print-electronic]. 2011; 6(5): e19880. PMID: 21611205, PMCID: PMC3096651, PII: PONE-D-11-01297, DOI: 10.1371/journal.pone.0019880, ISSN: 1932-6203.

Ray KC, Bell KM, Yan J, Gu G, Chung CH, Washington MK, Means AL. Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model. PLoS ONE. 2011; 6(2): e16786. PMID: 21311774, PMCID: PMC3032792, DOI: 10.1371/journal.pone.0016786, ISSN: 1932-6203.

Moreira RK, Chopp W, Washington.. The concept of hepatic artery-bile duct parallelism in the diagnosis of ductopenia in liver biopsy samples. Am J Surg Pathol. 2011; 35((3)): 392-403.

Anjani JA, Barthel JS, Bentrem DJ, DAmico TA, Das P, Denlinger CS, Fuchs CS, Gerdes H, Glasgow RE, Hayman, JA, Hofstetter WL, Ilson DH, Keswani RN, Kleinberg LR, Korn WM, Lockhart AC, Mulcahy MF, Orringer MB, Osarogiagbon RU, Posey JA, Sasson AR, Scott WJ, Shibata S, Strong VE, Varghese TK Jr., Warren G, Washington, MK, Willett C, Wright CD. Esophageal and esophagogastric junction cancers. J Natl Compr Canc Netw. 2011; 9((8)): 830-87.

Rich A, Toro TZ, Tanksley J, Fiske WH, Lind CD, Ayers GD, Piessevaux H, Washington MK, Coffey RJ. Distinguishing Ménétrier's disease from its mimics. Gut [print-electronic]. 2010 Dec; 59(12): 1617-24. PMID: 20926644, PMCID: PMC3020399, PII: gut.2010.220061, DOI: 10.1136/gut.2010.220061, ISSN: 1468-3288.

Schneider BG, Peng DF, Camargo MC, Piazuelo MB, Sicinschi LA, Mera R, Romero-Gallo J, Delgado AG, Bravo LE, Wilson KT, Peek RM, Correa P, El-Rifai W. Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer. Int. J. Cancer. 2010 Dec 12/1/2010; 127(11): 2588-97. PMID: 20178103, PMCID: PMC2916942, DOI: 10.1002/ijc.25274, ISSN: 1097-0215.

Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan JL, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, Sun ZW, Xia F, Holson EB, Khabele D, Hiebert SW. Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell. 2010 Nov 11/16/2010; 18(5): 436-47. PMID: 21075309, PMCID: PMC3004468, PII: S1535-6108(10)00424-1, DOI: 10.1016/j.ccr.2010.10.022, ISSN: 1878-3686.

Vilgelm AE, Hong SM, Washington MK, Wei J, Chen H, El-Rifai W, Zaika A. Characterization of ¿Np73 expression and regulation in gastric and esophageal tumors. Oncogene [print-electronic]. 2010 Oct 10/28/2010; 29(43): 5861-8. PMID: 20676143, PMCID: PMC4152004, PII: onc2010319, DOI: 10.1038/onc.2010.319, ISSN: 1476-5594.

Wei J, Nagy TA, Vilgelm A, Zaika E, Ogden SR, Romero-Gallo J, Piazuelo MB, Correa P, Washington MK, El-Rifai W, Peek RM, Zaika A. Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells. Gastroenterology [print-electronic]. 2010 Oct; 139(4): 1333-43. PMID: 20547161, PMCID: PMC2949494, PII: S0016-5085(10)00877-2, DOI: 10.1053/j.gastro.2010.06.018, ISSN: 1528-0012.

Vaezi MF, Slaughter JC, Smith BS, Washington MK, Jerome WG, Garrett CG, Hagaman D, Goutte M. Dilated intercellular space in chronic laryngitis and gastro-oesophageal reflux disease: at baseline and post-lansoprazole therapy. Aliment. Pharmacol. Ther. 2010 Oct; 32(7): 916-24. PMID: 20735783, DOI: 10.1111/j.1365-2036.2010.04420.x, ISSN: 1365-2036.

Soutto M, Peng D, Razvi M, Ruemmele P, Hartmann A, Roessner A, Schneider-Stock R, El-Rifai W. Epigenetic and genetic silencing of CHFR in esophageal adenocarcinomas. Cancer. 2010 Sep 9/1/2010; 116(17): 4033-42. PMID: 20564104, PMCID: PMC2930066, DOI: 10.1002/cncr.25151, ISSN: 0008-543X.

Nagaraj NS, Smith JJ, Revetta F, Washington MK, Merchant NB. Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis. Mol. Cancer Ther [print-electronic]. 2010 Aug; 9(8): 2322-32. PMID: 20682659, PMCID: PMC3449211, PII: 1535-7163.MCT-09-1212, DOI: 10.1158/1535-7163.MCT-09-1212, ISSN: 1538-8514.

Mukherjee K, Peng D, Brifkani Z, Belkhiri A, Pera M, Koyama T, Koehler EA, Revetta FL, Washington MK, El-Rifai W. Dopamine and cAMP regulated phosphoprotein MW 32 kDa is overexpressed in early stages of gastric tumorigenesis. Surgery [print-electronic]. 2010 Aug; 148(2): 354-63. PMID: 20580047, PMCID: PMC2919779, PII: S0039-6060(10)00274-6, DOI: 10.1016/j.surg.2010.05.011, ISSN: 1532-7361.

Miles S, Piazuelo MB, Semino-Mora C, Washington MK, Dubois A, Peek RM, Correa P, Merrell DS. Detailed in vivo analysis of the role of Helicobacter pylori Fur in colonization and disease. Infect. Immun [print-electronic]. 2010 Jul; 78(7): 3073-82. PMID: 20421381, PMCID: PMC2897407, PII: IAI.00190-10, DOI: 10.1128/IAI.00190-10, ISSN: 1098-5522.

Blaine SA, Ray KC, Anunobi R, Gannon MA, Washington MK, Means AL. Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling. Development [print-electronic]. 2010 Jul; 137(14): 2289-96. PMID: 20534672, PMCID: PMC2889602, PII: dev.048421, DOI: 10.1242/dev.048421, ISSN: 1477-9129.

Smalley-Freed WG, Efimov A, Burnett PE, Short SP, Davis MA, Gumucio DL, Washington MK, Coffey RJ, Reynolds AB. P120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. J. Clin. Invest [print-electronic]. 2010 Jun; 120(6): 1824-35. PMID: 20484816, PMCID: PMC2877948, PII: 41414, DOI: 10.1172/JCI41414, ISSN: 1558-8238.

Sparks EE, Huppert KA, Brown MA, Washington MK, Huppert SS. Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology. 2010 Apr; 51(4): 1391-400. PMID: 20069650, PMCID: PMC2995854, DOI: 10.1002/hep.23431, ISSN: 1527-3350.

Washington MK, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Vauthey JN, . Protocol for the examination of specimens from patients with carcinoma of the distal extrahepatic bile ducts. Arch. Pathol. Lab. Med. 2010 Apr; 134(4): e8-13. PMID: 20367298, PII: 10.1043/1543-2165-134.4.e8, DOI: 10.1043/1543-2165-134.4.e8, ISSN: 1543-2165.

Washington MK, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Vauthey JN, . Protocol for the examination of specimens from patients with carcinoma of the perihilar bile ducts. Arch. Pathol. Lab. Med. 2010 Apr; 134(4): e19-24. PMID: 20367295, PII: 10.1043/1543-2165-134.4.e19, DOI: 10.1043/1543-2165-134.4.e19, ISSN: 1543-2165.

Washington MK, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Vauthey JN, . Protocol for the examination of specimens from patients with carcinoma of the intrahepatic bile ducts. Arch. Pathol. Lab. Med. 2010 Apr; 134(4): e14-8. PMID: 20367294, PII: 10.1043/1543-2165-134.4.e14, DOI: 10.1043/1543-2165-134.4.e14, ISSN: 1543-2165.

Smith JJ, Deane NG, Wu F, Merchant NB, Zhang B, Jiang A, Lu P, Johnson JC, Schmidt C, Bailey CE, Eschrich S, Kis C, Levy S, Washington MK, Heslin MJ, Coffey RJ, Yeatman TJ, Shyr Y, Beauchamp RD. Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology [print-electronic]. 2010 Mar; 138(3): 958-68. PMID: 19914252, PMCID: PMC3388775, PII: S0016-5085(09)01964-7, DOI: 10.1053/j.gastro.2009.11.005, ISSN: 1528-0012.

Vilgelm AE, Washington MK, Wei J, Chen H, Prassolov VS, Zaika AI. Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors. Mol. Cancer Ther [print-electronic]. 2010 Mar; 9(3): 693-705. PMID: 20197393, PMCID: PMC2838189, PII: 1535-7163.MCT-09-0912, DOI: 10.1158/1535-7163.MCT-09-0912, ISSN: 1538-8514.

Washington MK, Tang LH, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, . Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the stomach. Arch. Pathol. Lab. Med. 2010 Feb; 134(2): 187-91. PMID: 20121605, PII: 10.1043/1543-2165-134.2.187, DOI: 10.1043/1543-2165-134.2.187, ISSN: 1543-2165.

Washington MK, Tang LH, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, . Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the small intestine and ampulla. Arch. Pathol. Lab. Med. 2010 Feb; 134(2): 181-6. PMID: 20121604, PII: 10.1043/1543-2165-134.2.181, DOI: 10.1043/1543-2165-134.2.181, ISSN: 1543-2165.

Washington MK, Tang LH, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, . Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the colon and rectum. Arch. Pathol. Lab. Med. 2010 Feb; 134(2): 176-80. PMID: 20121603, PII: 10.1043/1543-2165-134.2.176, DOI: 10.1043/1543-2165-134.2.176, ISSN: 1543-2165.

Washington MK, Tang LH, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, . Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the appendix. Arch. Pathol. Lab. Med. 2010 Feb; 134(2): 171-5. PMID: 20121602, PII: 10.1043/1543-2165-134.2.171, DOI: 10.1043/1543-2165-134.2.171, ISSN: 1543-2165.

Ogden SR, Noto JM, Allen SS, Patel DA, Romero-Gallo J, Washington MK, Fingleton B, Israel DA, Lewis ND, Wilson KT, Chaturvedi R, Zhao Z, Shyr Y, Peek RM. Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice. Cancer Res. 2010 Jan 1/1/2010; 70(1): 30-5. PMID: 20048070, PMCID: PMC2804939, PII: 0008-5472.CAN-09-2899, DOI: 10.1158/0008-5472.CAN-09-2899, ISSN: 1538-7445.

Vangamudi B, Peng DF, Cai Q, El-Rifai W, Zheng W, Belkhiri A. T-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer. Mol. Cancer. 2010; 9: 240. PMID: 20836878, PMCID: PMC2945963, PII: 1476-4598-9-240, DOI: 10.1186/1476-4598-9-240, ISSN: 1476-4598.

Zhang H, Ables ET, Pope CF, Washington MK, Hipkens S, Means AL, Path G, Seufert J, Costa RH, Leiter AB, Magnuson MA, Gannon M. Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation. Mech. Dev [print-electronic]. 2009 Dec; 126(11-12): 958-73. PMID: 19766716, PMCID: PMC2783291, PII: S0925-4773(09)01453-1, DOI: 10.1016/j.mod.2009.09.006, ISSN: 1872-6356.

Fiske WH, Tanksley J, Nam KT, Goldenring JR, Slebos RJ, Liebler DC, Abtahi AM, La Fleur B, Ayers GD, Lind CD, Washington MK, Coffey RJ. Efficacy of cetuximab in the treatment of Menetrier's disease. Sci Transl Med. 2009 Nov 11/25/2009; 1(8): 8ra18. PMID: 20368185, PMCID: PMC3638759, PII: 1/8/8ra18, DOI: 10.1126/scitranslmed.3000320, ISSN: 1946-6242.

Algood HM, Allen SS, Washington MK, Peek RM, Miller GG, Cover TL. Regulation of gastric B cell recruitment is dependent on IL-17 receptor A signaling in a model of chronic bacterial infection. J. Immunol [print-electronic]. 2009 Nov 11/1/2009; 183(9): 5837-46. PMID: 19812196, PMCID: PMC2834183, PII: jimmunol.0901206, DOI: 10.4049/jimmunol.0901206, ISSN: 1550-6606.

Ray KC, Blaine SA, Washington MK, Braun AH, Singh AB, Harris RC, Harding PA, Coffey RJ, Means AL. Transmembrane and soluble isoforms of heparin-binding epidermal growth factor-like growth factor regulate distinct processes in the pancreas. Gastroenterology [print-electronic]. 2009 Nov; 137(5): 1785-94. PMID: 19689925, PMCID: PMC2767440, PII: S0016-5085(09)01399-7, DOI: 10.1053/j.gastro.2009.07.067, ISSN: 1528-0012.

Washington MK, Berlin J, Branton P, Burgart LJ, Carter DK, Fitzgibbons PL, Halling K, Frankel W, Jessup J, Kakar S, Minsky B, Nakhleh R, Compton CC, . Protocol for the examination of specimens from patients with primary carcinoma of the colon and rectum. Arch. Pathol. Lab. Med. 2009 Oct; 133(10): 1539-51. PMID: 19792043, PMCID: PMC2901838, PII: 2009-0313-CPR, DOI: 10.1043/1543-2165-133.10.1539, ISSN: 1543-2165.

Johnson EM, Doyle JD, Wetzel JD, McClung RP, Katunuma N, Chappell JD, Washington MK, Dermody TS. Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis. J. Virol [print-electronic]. 2009 Oct; 83(19): 9630-40. PMID: 19640986, PMCID: PMC2748054, PII: JVI.01095-09, DOI: 10.1128/JVI.01095-09, ISSN: 1098-5514.

Boomershine CS, Chamberlain A, Kendall P, Afshar-Sharif AR, Huang H, Washington MK, Lawson WE, Thomas JW, Blackwell TS, Bhowmick NA. Autoimmune pancreatitis results from loss of TGFbeta signalling in S100A4-positive dendritic cells. Gut [print-electronic]. 2009 Sep; 58(9): 1267-74. PMID: 19625278, PMCID: PMC2719085, PII: gut.2008.170779, DOI: 10.1136/gut.2008.170779, ISSN: 1468-3288.

Franco AT, Friedman DB, Nagy TA, Romero-Gallo J, Krishna U, Kendall A, Israel DA, Tegtmeyer N, Washington MK, Peek RM. Delineation of a carcinogenic Helicobacter pylori proteome. Mol. Cell Proteomics [print-electronic]. 2009 Aug; 8(8): 1947-58. PMID: 19470446, PMCID: PMC2722763, PII: M900139-MCP200, DOI: 10.1074/mcp.M900139-MCP200, ISSN: 1535-9484.

Sprung RW, Brock JW, Tanksley JP, Li M, Washington MK, Slebos RJ, Liebler DC. Equivalence of protein inventories obtained from formalin-fixed paraffin-embedded and frozen tissue in multidimensional liquid chromatography-tandem mass spectrometry shotgun proteomic analysis. Mol. Cell Proteomics [print-electronic]. 2009 Aug; 8(8): 1988-98. PMID: 19467989, PMCID: PMC2722776, PII: M800518-MCP200, DOI: 10.1074/mcp.M800518-MCP200, ISSN: 1535-9484.

VanSaun MN, Lee IK, Washington MK, Matrisian L, Gorden DL. High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model. Am. J. Pathol [print-electronic]. 2009 Jul; 175(1): 355-64. PMID: 19541928, PMCID: PMC2708821, PII: S0002-9440(10)60550-0, DOI: 10.2353/ajpath.2009.080703, ISSN: 1525-2191.

Xu BJ, Li J, Beauchamp RD, Shyr Y, Li M, Washington MK, Yeatman TJ, Whitehead RH, Coffey RJ, Caprioli RM. Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS. Mol. Cell Proteomics [print-electronic]. 2009 May; 8(5): 936-45. PMID: 19164278, PMCID: PMC2689774, PII: M800345-MCP200, DOI: 10.1074/mcp.M800345-MCP200, ISSN: 1535-9484.

Trobridge P, Knoblaugh S, Washington MK, Munoz NM, Tsuchiya KD, Rojas A, Song X, Ulrich CM, Sasazuki T, Shirasawa S, Grady WM. TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway. Gastroenterology [print-electronic]. 2009 May; 136(5): 1680-8.e7. PMID: 19208363, PMCID: PMC2782436, PII: S0016-5085(09)00170-X, DOI: 10.1053/j.gastro.2009.01.066, ISSN: 1528-0012.

Yan F, Cao H, Chaturvedi R, Krishna U, Hobbs SS, Dempsey PJ, Peek RM, Cover TL, Washington MK, Wilson KT, Polk DB. Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis. Gastroenterology [print-electronic]. 2009 Apr; 136(4): 1297-1307, e1. PMID: 19250983, PMCID: PMC2878739, PII: S0016-5085(08)02317-2, DOI: 10.1053/j.gastro.2008.12.059, ISSN: 1528-0012.

Cates JM, Byrd RH, Fohn LE, Tatsas AD, Washington MK, Black CC. Epithelial-mesenchymal transition markers in pancreatic ductal adenocarcinoma. Pancreas. 2009 Jan; 38(1): e1-6. PMID: 18766116, PMCID: PMC2882851, DOI: 10.1097/MPA.0b013e3181878b7f, ISSN: 1536-4828.

Peng DF, Razvi M, Chen H, Washington K, Roessner A, Schneider-Stock R, El-Rifai W. DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. Gut [print-electronic]. 2009 Jan; 58(1): 5-15. PMID: 18664505, PMCID: PMC2845391, PII: gut.2007.146290, DOI: 10.1136/gut.2007.146290, ISSN: 1468-3288.

Lee W, Belkhiri A, Lockhart AC, Merchant N, Glaeser H, Harris EI, Washington MK, Brunt EM, Zaika A, Kim RB, El-Rifai W. Overexpression of OATP1B3 confers apoptotic resistance in colon cancer. Cancer Res. 2008 Dec 12/15/2008; 68(24): 10315-23. PMID: 19074900, PMCID: PMC2605661, PII: 68/24/10315, DOI: 10.1158/0008-5472.CAN-08-1984, ISSN: 1538-7445.

Marcellin P, Heathcote EJ, Buti M, Gane E, de Man RA, Krastev Z, Germanidis G, Lee SS, Flisiak R, Kaita K, Manns M, Kotzev I, Tchernev K, Buggisch P, Weilert F, Kurdas OO, Shiffman ML, Trinh H, Washington MK, Sorbel J, Anderson J, Snow-Lampart A, Mondou E, Quinn J, Rousseau F. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N. Engl. J. Med. 2008 Dec 12/4/2008; 359(23): 2442-55. PMID: 19052126, PII: 359/23/2442, DOI: 10.1056/NEJMoa0802878, ISSN: 1533-4406.

Harris EI, Lewin DN, Wang HL, Lauwers GY, Srivastava A, Shyr Y, Shakhtour B, Revetta F, Washington MK. Lymphovascular invasion in colorectal cancer: an interobserver variability study. Am. J. Surg. Pathol. 2008 Dec; 32(12): 1816-21. PMID: 18779725, PMCID: PMC2605104, DOI: 10.1097/PAS.0b013e3181816083, ISSN: 1532-0979.

Manning HC, Merchant NB, Foutch AC, Virostko JM, Wyatt SK, Shah C, McKinley ET, Xie J, Mutic NJ, Washington MK, LaFleur B, Tantawy MN, Peterson TE, Ansari MS, Baldwin RM, Rothenberg ML, Bornhop DJ, Gore JC, Coffey RJ. Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. Clin. Cancer Res. 2008 Nov 11/15/2008; 14(22): 7413-22. PMID: 19010858, PMCID: PMC2657180, PII: 14/22/7413, DOI: 10.1158/1078-0432.CCR-08-0239, ISSN: 1078-0432.

Washington MK. Colorectal carcinoma: selected issues in pathologic examination and staging and determination of prognostic factors. Arch. Pathol. Lab. Med. 2008 Oct; 132(10): 1600-7. PMID: 18834218, PII: 2007-0515-RAR, DOI: 10.1043/1543-2165(2008)132[1600:CCSIIP]2.0.CO;2, ISSN: 1543-2165.

Ajani JA, Barthel JS, Bekaii-Saab T, Bentrem DJ, D'Amico TA, Fuchs CS, Gerdes H, Hayman JA, Hazard L, Ilson DH, Kleinberg LR, McAleer MF, Meropol NJ, Mulcahy MF, Orringer MB, Osarogiagbon RU, Posey JA, Sasson AR, Scott WJ, Shibata S, Strong VE, Swisher SG, Washington MK, Willett C, Wood DE, Wright CD, Yang G, . Esophageal cancer. J Natl Compr Canc Netw. 2008 Oct; 6(9): 818-49. PMID: 18926093.

Farmer TE, Williams CS, Washington MK, Hiebert SW. Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrity. J. Cell. Biochem. 2008 Aug 8/15/2008; 104(6): 2228-40. PMID: 18442038, PMCID: PMC3164503, DOI: 10.1002/jcb.21779, ISSN: 1097-4644.

Edelblum KL, Washington MK, Koyama T, Robine S, Baccarini M, Polk DB. Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB. Gastroenterology [print-electronic]. 2008 Aug; 135(2): 539-51. PMID: 18598699, PMCID: PMC2640938, PII: S0016-5085(08)00720-8, DOI: 10.1053/j.gastro.2008.04.025, ISSN: 1528-0012.

Belkhiri A, Dar AA, Peng DF, Razvi MH, Rinehart C, Arteaga CL, El-Rifai W. Expression of t-DARPP mediates trastuzumab resistance in breast cancer cells. Clin. Cancer Res [print-electronic]. 2008 Jul 7/15/2008; 14(14): 4564-71. PMID: 18579663, PMCID: PMC2842884, PII: 1078-0432.CCR-08-0121, DOI: 10.1158/1078-0432.CCR-08-0121, ISSN: 1078-0432.

Washington MK, Berlin J, Branton PA, Burgart LJ, Carter DK, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Compton CC, . Protocol for the examination of specimens from patients with primary carcinomas of the colon and rectum. Arch. Pathol. Lab. Med. 2008 Jul; 132(7): 1182-93. PMID: 18605770, PII: 2008-0008-CP, DOI: 10.1043/1543-2165(2008)132[1182:PFTEOS]2.0.CO;2.

Rojas A, Meherem S, Kim YH, Washington MK, Willis JE, Markowitz SD, Grady WM. The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer. Int. J. Cancer. 2008 Jul 7/1/2008; 123(1): 14-21. PMID: 18425817, PMCID: PMC2777657, DOI: 10.1002/ijc.23608, ISSN: 1097-0215.

Grady WM, Parkin RK, Mitchell PS, Lee JH, Kim YH, Tsuchiya KD, Washington MK, Paraskeva C, Willson JK, Kaz AM, Kroh EM, Allen A, Fritz BR, Markowitz SD, Tewari M. Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene [print-electronic]. 2008 Jun 6/19/2008; 27(27): 3880-8. PMID: 18264139, PII: onc200810, DOI: 10.1038/onc.2008.10, ISSN: 1476-5594.

Wei J, O'Brien D, Vilgelm A, Piazuelo MB, Correa P, Washington MK, El-Rifai W, Peek RM, Zaika A. Interaction of Helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family. Gastroenterology [print-electronic]. 2008 May; 134(5): 1412-23. PMID: 18343378, PMCID: PMC2430883, PII: S0016-5085(08)00178-9, DOI: 10.1053/j.gastro.2008.01.072, ISSN: 1528-0012.

Dar AA, Zaika A, Piazuelo MB, Correa P, Koyama T, Belkhiri A, Washington K, Castells A, Pera M, El-Rifai W. Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions. Cancer. 2008 Apr 4/15/2008; 112(8): 1688-98. PMID: 18311783, PMCID: PMC4030394, DOI: 10.1002/cncr.23371, ISSN: 0008-543X.

Vilgelm A, Wei JX, Piazuelo MB, Washington MK, Prassolov V, El-Rifai W, Zaika A. DeltaNp73alpha regulates MDR1 expression by inhibiting p53 function. Oncogene [print-electronic]. 2008 Apr 4/3/2008; 27(15): 2170-6. PMID: 17952118, PMCID: PMC4066670, PII: 1210862, DOI: 10.1038/sj.onc.1210862, ISSN: 1476-5594.

Peng D, Sheta EA, Powell SM, Moskaluk CA, Washington K, Goldknopf IL, El-Rifai W. Alterations in Barrett's-related adenocarcinomas: a proteomic approach. Int. J. Cancer. 2008 Mar 3/15/2008; 122(6): 1303-10. PMID: 18000824, DOI: 10.1002/ijc.23258, ISSN: 1097-0215.

Romero-Gallo J, Harris EJ, Krishna U, Washington MK, Perez-Perez GI, Peek RM. Effect of Helicobacter pylori eradication on gastric carcinogenesis. Lab. Invest [print-electronic]. 2008 Mar; 88(3): 328-36. PMID: 18180700, PMCID: PMC2833422, PII: 3700719, DOI: 10.1038/labinvest.3700719, ISSN: 1530-0307.

Merchant NB, Voskresensky I, Rogers CM, Lafleur B, Dempsey PJ, Graves-Deal R, Revetta F, Foutch AC, Rothenberg ML, Washington MK, Coffey RJ. TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. Clin. Cancer Res. 2008 Feb 2/15/2008; 14(4): 1182-91. PMID: 18281553, PMCID: PMC3718282, PII: 14/4/1182, DOI: 10.1158/1078-0432.CCR-07-1216, ISSN: 1078-0432.

Thompson BJ, Washington MK, Kurre U, Singh M, Rula EY, Emeson RB. Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis. Dig. Dis. Sci [print-electronic]. 2008 Jan; 53(1): 229-41. PMID: 17530400, DOI: 10.1007/s10620-007-9848-7, ISSN: 0163-2116.

Edgerton ME, Morrison C, LiVolsi VA, Moskaluk CA, Qualman SJ, Washington MK, Grizzle WE. A standards based ontological approach to information handling for use by organizations providing human tissue for research. Cancer Inform [print-electronic]. 2008; 6: 127-37. PMID: 19259407, PMCID: PMC2623300, ISSN: 1176-9351.

Shao J, Washington MK, Saxena R, Sheng H. Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse: roles of osteopontin. Carcinogenesis [print-electronic]. 2007 Dec; 28(12): 2476-83. PMID: 17693663, PII: bgm186, DOI: 10.1093/carcin/bgm186, ISSN: 1460-2180.

Barnes SL, Lyshchik A, Washington MK, Gore JC, Miga MI. Development of a mechanical testing assay for fibrotic murine liver. Med Phys. 2007 Nov; 34(11): 4439-50. PMID: 18072508, PMCID: PMC2442892, ISSN: 0094-2405.

M'Koma AE, Wise PE, Muldoon RL, Schwartz DA, Washington MK, Herline AJ. Evolution of the restorative proctocolectomy and its effects on gastrointestinal hormones. Int J Colorectal Dis [print-electronic]. 2007 Oct; 22(10): 1143-63. PMID: 17576578, DOI: 10.1007/s00384-007-0331-x, ISSN: 0179-1958.

Razvi MH, Peng D, Dar AA, Powell SM, Frierson HF, Moskaluk CA, Washington K, El-Rifai W. Transcriptional oncogenomic hot spots in Barrett's adenocarcinomas: serial analysis of gene expression. Genes Chromosomes Cancer. 2007 Oct; 46(10): 914-28. PMID: 17636545, DOI: 10.1002/gcc.20479, ISSN: 1045-2257.

Bamborough P, Angell RM, Bhamra I, Brown D, Bull J, Christopher JA, Cooper AW, Fazal LH, Giordano I, Hind L, Patel VK, Ranshaw LE, Sims MJ, Skone PA, Smith KJ, Vickerstaff E, Washington M. N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: indazoles as phenol isosteres with improved pharmacokinetics. Bioorg. Med. Chem. Lett [print-electronic]. 2007 Aug 8/1/2007; 17(15): 4363-8. PMID: 17600705, PII: S0960-894X(07)00449-0, DOI: 10.1016/j.bmcl.2007.04.029, ISSN: 0960-894X.

Felts AS, Ji C, Stafford JB, Crews BC, Kingsley PJ, Rouzer CA, Washington MK, Subbaramaiah K, Siegel BS, Young SM, Dannenberg AJ, Marnett LJ. Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology [letter]. ACS Chem. Biol [print-electronic]. 2007 Jul 7/20/2007; 2(7): 479-83. PMID: 17602619, DOI: 10.1021/cb700077z, ISSN: 1554-8937.

Li JQ, Xu BJ, Shakhtour B, Deane N, Merchant N, Heslin MJ, Washington K, Coffey RJ, Beauchamp RD, Shyr Y, Billheimer D. Variability of in situ proteomic profiling and implications for study design in colorectal tumors. Int. J. Oncol. 2007 Jul; 31(1): 103-11. PMID: 17549410, ISSN: 1019-6439.

Deane NG, Manning HC, Foutch AC, Washington MK, Aronow BJ, Bornhop DJ, Coffey RJ. Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammation. Mol. Cancer Res. 2007 Apr; 5(4): 341-9. PMID: 17426249, PII: 5/4/341, DOI: 10.1158/1541-7786.MCR-06-0225, ISSN: 1541-7786.

Finegold MJ, Lopez-Terrada DH, Bowen J, Washington MK, Qualman SJ, . Protocol for the examination of specimens from pediatric patients with hepatoblastoma. Arch. Pathol. Lab. Med. 2007 Apr; 131(4): 520-9. PMID: 17425379, PII: CP6-0381, DOI: 10.1043/1543-2165(2007)131[520:PFTEOS]2.0.CO;2.

Shiou SR, Singh AB, Moorthy K, Datta PK, Washington MK, Beauchamp RD, Dhawan P. Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. Cancer Res. 2007 Feb 2/15/2007; 67(4): 1571-9. PMID: 17308096, PII: 67/4/1571, DOI: 10.1158/0008-5472.CAN-06-1680, ISSN: 0008-5472.

Washington MK. Autoimmune liver disease: overlap and outliers. Mod. Pathol. 2007 Feb; 20 Suppl 1: S15-30. PMID: 17486048, PII: 3800684, DOI: 10.1038/modpathol.3800684, ISSN: 0893-3952.

Yan F, Cao H, Cover TL, Whitehead R, Washington MK, Polk DB. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology [print-electronic]. 2007 Feb; 132(2): 562-75. PMID: 17258729, PMCID: PMC3036990, PII: S0016-5085(06)02477-2, DOI: 10.1053/j.gastro.2006.11.022, ISSN: 0016-5085.

Coffey RJ, Washington MK, Corless CL, Heinrich MC. Ménétrier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach. J. Clin. Invest. 2007 Jan; 117(1): 70-80. PMID: 17200708, PMCID: PMC1716220, DOI: 10.1172/JCI30491, ISSN: 0021-9738.

Johnson JC, Schmidt CR, Shrubsole MJ, Billheimer DD, Joshi PR, Morrow JD, Heslin MJ, Washington MK, Ness RM, Zheng W, Schwartz DA, Coffey RJ, Beauchamp RD, Merchant NB. Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin. Gastroenterol. Hepatol [print-electronic]. 2006 Nov; 4(11): 1358-65. PMID: 16996805, PII: S1542-3565(06)00772-5, DOI: 10.1016/j.cgh.2006.07.015, ISSN: 1542-3565.

Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, Sozmen EG, Madison BB, Pozzi A, Moon RT, Moses HL, Grady WM. Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Res. 2006 Oct 10/15/2006; 66(20): 9837-44. PMID: 17047044, PII: 66/20/9837, DOI: 10.1158/0008-5472.CAN-06-0890, ISSN: 0008-5472.

Lee OJ, Hong SM, Razvi MH, Peng D, Powell SM, Smoklin M, Moskaluk CA, El-Rifai W. Expression of calcium-binding proteins S100A2 and S100A4 in Barrett's adenocarcinomas. Neoplasia. 2006 Oct; 8(10): 843-50. PMID: 17032501, PMCID: PMC1715926, DOI: 10.1593/neo.06481, ISSN: 1476-5586.

Leys CM, Nomura S, Rudzinski E, Kaminishi M, Montgomery E, Washington MK, Goldenring JR. Expression of Pdx-1 in human gastric metaplasia and gastric adenocarcinoma. Hum. Pathol [print-electronic]. 2006 Sep; 37(9): 1162-8. PMID: 16938521, PII: S0046-8177(06)00219-X, DOI: 10.1016/j.humpath.2006.04.011, ISSN: 0046-8177.

Su Y, Shrubsole MJ, Ness RM, Cai Q, Kataoka N, Washington K, Zheng W. Immunohistochemical expressions of Ki-67, cyclin D1, beta-catenin, cyclooxygenase-2, and epidermal growth factor receptor in human colorectal adenoma: a validation study of tissue microarrays. Cancer Epidemiol. Biomarkers Prev. 2006 Sep; 15(9): 1719-26. PMID: 16985035, PII: 15/9/1719, DOI: 10.1158/1055-9965.EPI-05-0946, ISSN: 1055-9965.

Martinez JA, Williams CS, Amann JM, Ellis TC, Moreno-Miralles I, Washington MK, Gregoli P, Hiebert SW. Deletion of Mtgr1 sensitizes the colonic epithelium to dextran sodium sulfate-induced colitis. Gastroenterology. 2006 Aug; 131(2): 579-88. PMID: 16890610, PII: S0016-5085(06)01238-8, DOI: 10.1053/j.gastro.2006.06.009, ISSN: 0016-5085.

Kim YH, Petko Z, Dzieciatkowski S, Lin L, Ghiassi M, Stain S, Chapman WC, Washington MK, Willis J, Markowitz SD, Grady WM. CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer. Genes Chromosomes Cancer. 2006 Aug; 45(8): 781-9. PMID: 16708352, DOI: 10.1002/gcc.20341, ISSN: 1045-2257.

Ye C, Shrubsole MJ, Cai Q, Ness R, Grady WM, Smalley W, Cai H, Washington K, Zheng W. Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas. Oncol. Rep. 2006 Aug; 16(2): 429-35. PMID: 16820927, ISSN: 1021-335X.

Halder SK, Anumanthan G, Maddula R, Mann J, Chytil A, Gonzalez AL, Washington MK, Moses HL, Beauchamp RD, Datta PK. Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis. Cancer Res. 2006 Jun 6/15/2006; 66(12): 6156-66. PMID: 16778189, PII: 66/12/6156, DOI: 10.1158/0008-5472.CAN-05-3261, ISSN: 0008-5472.

Welch DC, Wirth PS, Goldenring JR, Ness E, Jagasia M, Washington K. Gastric graft-versus-host disease revisited: does proton pump inhibitor therapy affect endoscopic gastric biopsy interpretation?. Am. J. Surg. Pathol. 2006 Apr; 30(4): 444-9. PMID: 16625089, PII: 00000478-200604000-00003, ISSN: 0147-5185.

Gray KD, Ballard BR, Washington MK, Belue R, Grady WM, Chapman WC, Stain SC. Do adverse histopathologic findings in colorectal cancer patients explain disparate outcomes?. J Natl Med Assoc. 2006 Mar; 98(3): 348-51. PMID: 16573297, PMCID: PMC2576115, ISSN: 1943-4693.

Lim SG, Ng TM, Kung N, Krastev Z, Volfova M, Husa P, Lee SS, Chan S, Shiffman ML, Washington MK, Rigney A, Anderson J, Mondou E, Snow A, Sorbel J, Guan R, Rousseau F, . A double-blind placebo-controlled study of emtricitabine in chronic hepatitis B. Arch. Intern. Med. 2006 Jan 1/9/2006; 166(1): 49-56. PMID: 16401810, PII: 166/1/49, DOI: 10.1001/archinte.166.1.49, ISSN: 0003-9926.

Shulman HM, Kleiner D, Lee SJ, Morton T, Pavletic SZ, Farmer E, Moresi JM, Greenson J, Janin A, Martin PJ, McDonald G, Flowers ME, Turner M, Atkinson J, Lefkowitch J, Washington MK, Prieto VG, Kim SK, Argenyi Z, Diwan AH, Rashid A, Hiatt K, Couriel D, Schultz K, Hymes S, Vogelsang GB. Histopathologic diagnosis of chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. Pathology Working Group Report. Biol. Blood Marrow Transplant. 2006 Jan; 12(1): 31-47. PMID: 16399567, PII: S1083-8791(05)00722-6, DOI: 10.1016/j.bbmt.2005.10.023, ISSN: 1083-8791.

Smith LH, Dixon JD, Stringham JR, Eren M, Elokdah H, Crandall DL, Washington K, Vaughan DE. Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis. Blood [print-electronic]. 2006 Jan 1/1/2006; 107(1): 132-4. PMID: 16160004, PMCID: PMC1895352, PII: 2005-07-2681, DOI: 10.1182/blood-2005-07-2681, ISSN: 0006-4971.

Washington K. Hepatic iron deposition: new observations in non-HFE hemochromatosis [editorial]. Advances in Anatomic Pathology. 2006; 13((6)): 341-2.

[place unknown: publisher unknown]; 2006.

[place unknown: publisher unknown]; 2006.

Rothenberg ML, LaFleur B, Levy DE, Washington MK, Morgan-Meadows SL, Ramanathan RK, Berlin JD, Benson AB, Coffey RJ. Randomized phase II trial of the clinical and biological effects of two dose levels of gefitinib in patients with recurrent colorectal adenocarcinoma. J. Clin. Oncol. 2005 Dec 12/20/2005; 23(36): 9265-74. PMID: 16361624, PII: 23/36/9265, DOI: 10.1200/JCO.2005.03.0536, ISSN: 0732-183X.

Amann JM, Chyla BJ, Ellis TC, Martinez A, Moore AC, Franklin JL, McGhee L, Meyers S, Ohm JE, Luce KS, Ouelette AJ, Washington MK, Thompson MA, King D, Gautam S, Coffey RJ, Whitehead RH, Hiebert SW. Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Mol. Cell. Biol. 2005 Nov; 25(21): 9576-85. PMID: 16227606, PMCID: PMC1265807, PII: 25/21/9576, DOI: 10.1128/MCB.25.21.9576-9585.2005, ISSN: 0270-7306.

Robert ME, Washington MK, Lee JR, Goldenring JR, Bronner MP, Goldblum JR, Greenson JK, Haber MM, Hart JA, Lamps LW, Lauwers GY, Lewin D, Lazenby AJ, Montgomery E, Crawford JM. Rab11a immunohistochemical analysis does not distinguish indefinite, low-, and high-grade dysplasia in Barrett esophagus. Am. J. Clin. Pathol. 2005 Oct; 124(4): 519-27. PMID: 16146818, PII: 7X4GAXT15H50B48P, DOI: 10.1309/7X4GAXT15H50B48P, ISSN: 0002-9173.

Franco AT, Israel DA, Washington MK, Krishna U, Fox JG, Rogers AB, Neish AS, Collier-Hyams L, Perez-Perez GI, Hatakeyama M, Whitehead R, Gaus K, O'Brien DP, Romero-Gallo J, Peek RM. Activation of beta-catenin by carcinogenic Helicobacter pylori. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2005 Jul 7/26/2005; 102(30): 10646-51. PMID: 16027366, PMCID: PMC1180811, PII: 0504927102, DOI: 10.1073/pnas.0504927102, ISSN: 0027-8424.

Bao P, Welch DC, Washington MK, Herline AJ. Resection of mesenteric inflammatory veno-occlusive disease causing ischemic colitis. J. Gastrointest. Surg. 2005 Jul; 9(6): 812-7. PMID: 15985236, PII: S1091-255X(05)00349-5, DOI: 10.1016/j.gassur.2005.02.002, ISSN: 1091-255X.

Dhawan P, Singh AB, Deane NG, No Y, Shiou SR, Schmidt C, Neff J, Washington MK, Beauchamp RD. Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J. Clin. Invest [print-electronic]. 2005 Jul; 115(7): 1765-76. PMID: 15965503, PMCID: PMC1150288, DOI: 10.1172/JCI24543, ISSN: 0021-9738.

Settle SH, Washington K, Lind C, Itzkowitz S, Fiske WH, Burdick JS, Jerome WG, Ray M, Weinstein W, Coffey RJ. Chronic treatment of Ménétrier's disease with Erbitux: clinical efficacy and insight into pathophysiology. Clin. Gastroenterol. Hepatol. 2005 Jul; 3(7): 654-9. PMID: 16206497, ISSN: 1542-3565.

Washington K. Update on post-liver transplantation infections, malignancies, and surgical complications. Adv Anat Pathol. 2005 Jul; 12(4): 221-6. PMID: 16096384, PII: 00125480-200507000-00006, ISSN: 1072-4109.

Huang W, Zhang J, Washington M, Liu J, Parant JM, Lozano G, Moore DD. Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor. Mol. Endocrinol [print-electronic]. 2005 Jun; 19(6): 1646-53. PMID: 15831521, PII: me.2004-0520, DOI: 10.1210/me.2004-0520, ISSN: 0888-8809.

Thliveris AT, Halberg RB, Clipson L, Dove WF, Sullivan R, Washington MK, Stanhope S, Newton MA. Polyclonality of familial murine adenomas: analyses of mouse chimeras with low tumor multiplicity suggest short-range interactions. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2005 May 5/10/2005; 102(19): 6960-5. PMID: 15870186, PMCID: PMC1100801, PII: 0502662102, DOI: 10.1073/pnas.0502662102, ISSN: 0027-8424.

Thomas KT, Welch D, Trueblood A, Sulur P, Wise P, Gorden DL, Chari RS, Wright JK, Washington K, Pinson CW. Effective treatment of biliary cystadenoma. Ann. Surg. 2005 May; 241(5): 769-73; discussion 773. PMID: 15849512, PMCID: PMC1357131, PII: 00000658-200505000-00010, ISSN: 0003-4932.

Hansel DE, Dhara S, Huang RC, Ashfaq R, Deasel M, Shimada Y, Bernstein HS, Harmon J, Brock M, Forastiere A, Washington MK, Maitra A, Montgomery E. CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target. Am. J. Surg. Pathol. 2005 Mar; 29(3): 390-9. PMID: 15725809, PII: 00000478-200503000-00014, ISSN: 0147-5185.

Petko Z, Ghiassi M, Shuber A, Gorham J, Smalley W, Washington MK, Schultenover S, Gautam S, Markowitz SD, Grady WM. Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps. Clin. Cancer Res. 2005 Feb 2/1/2005; 11(3): 1203-9. PMID: 15709190, PII: 11/3/1203, ISSN: 1078-0432.

Park YK, Franklin JL, Settle SH, Levy SE, Chung E, Jeyakumar LH, Shyr Y, Washington MK, Whitehead RH, Aronow BJ, Coffey RJ. Gene expression profile analysis of mouse colon embryonic development. Genesis. 2005 Jan; 41(1): 1-12. PMID: 15645444, DOI: 10.1002/gene.20088, ISSN: 1526-954X.

Yan F, John SK, Wilson G, Jones DS, Washington MK, Polk DB. Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. J. Clin. Invest. 2004 Nov; 114(9): 1272-80. PMID: 15520859, PMCID: PMC524224, DOI: 10.1172/JCI21022, ISSN: 0021-9738.

Buttemere CR, Chari RS, Anderson CD, Washington MK, Mahadevan-Jansen A, Lin WC. In vivo assessment of thermal damage in the liver using optical spectroscopy. J Biomed Opt. 2004 Sep; 9(5): 1018-27. PMID: 15447024, DOI: 10.1117/1.1779627, ISSN: 1083-3668.

Anderson CD, Lin WC, Buttemere CR, Washington MK, Mahadevan-Jansen A, Pierce J, Nicoud IB, Pinson CW, Chari RS. Real-time spectroscopic assessment of thermal damage: implications for radiofrequency ablation. J. Gastrointest. Surg. 2004 Sep; 8(6): 660-9. PMID: 15358325, PII: S1091255X04001787, DOI: 10.1016/j.gassur.2004.04.009, ISSN: 1091-255X.

Biswas S, Chytil A, Washington K, Romero-Gallo J, Gorska AE, Wirth PS, Gautam S, Moses HL, Grady WM. Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer. Cancer Res. 2004 Jul 7/15/2004; 64(14): 4687-92. PMID: 15256431, PII: 64/14/4687, DOI: 10.1158/0008-5472.CAN-03-3255, ISSN: 0008-5472.

Qualman SJ, France M, Grizzle WE, LiVolsi VA, Moskaluk CA, Ramirez NC, Washington MK. Establishing a tumour bank: banking, informatics and ethics. Br. J. Cancer. 2004 Mar 3/22/2004; 90(6): 1115-9. PMID: 15026787, PMCID: PMC2409638, PII: 6601678, DOI: 10.1038/sj.bjc.6601678, ISSN: 0007-0920.

Deane NG, Lee H, Hamaamen J, Ruley A, Washington MK, LaFleur B, Thorgeirsson SS, Price R, Beauchamp RD. Enhanced tumor formation in cyclin D1 x transforming growth factor beta1 double transgenic mice with characterization by magnetic resonance imaging. Cancer Res. 2004 Feb 2/15/2004; 64(4): 1315-22. PMID: 14973059, ISSN: 0008-5472.

Bhowmick NA, Chytil A, Plieth D, Gorska AE, Dumont N, Shappell S, Washington MK, Neilson EG, Moses HL. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science. 2004 Feb 2/6/2004; 303(5659): 848-51. PMID: 14764882, PII: 303/5659/848, DOI: 10.1126/science.1090922, ISSN: 1095-9203.

Scoggins CR, Moore D, Washington K, Wright JK, Chari RS. Supra-elevated CA 19-9 in a benign hepatic cyst adenoma. HPB (Oxford). 2004; 6(1): 43-4. PMID: 18333046, PMCID: PMC2020653, DOI: 10.1080/13651820310015806, ISSN: 1365-182X.

Stack E, Washington K, Avant GR, Eisen GM. Cytomegalovirus enteritis in common variable immunodeficiency. South. Med. J. 2004 Jan; 97(1): 96-101. PMID: 14746434, DOI: 10.1097/01.SMJ.0000053461.31030.D7, ISSN: 0038-4348.

Parker MA, Deane NG, Thompson EA, Whitehead RH, Mithani SK, Washington MK, Datta PK, Dixon DA, Beauchamp RD. Over-expression of cyclin D1 regulates Cdk4 protein synthesis. Cell Prolif. 2003 Dec; 36(6): 347-60. PMID: 14710852, ISSN: 0960-7722.

Schmidt CR, Washington MK, Gi YJ, Coffey RJ, Beauchamp RD, Pearson AS. Dysregulation of E-cadherin by oncogenic Ras in intestinal epithelial cells is blocked by inhibiting MAP kinase. Am. J. Surg. 2003 Nov; 186(5): 426-30. PMID: 14599601, PII: S0002961003003271, ISSN: 0002-9610.

Crawford HC, Krishna US, Israel DA, Matrisian LM, Washington MK, Peek RM. Helicobacter pylori strain-selective induction of matrix metalloproteinase-7 in vitro and within gastric mucosa. Gastroenterology. 2003 Oct; 125(4): 1125-36. PMID: 14517796, PII: S001650850301206X, ISSN: 0016-5085.

Wudel LJ, Allos TM, Washington MK, Sheller JR, Chapman WC. Multi-organ inflammation after hepatic cryoablation in BALB/c mice. J. Surg. Res. 2003 Jun 6/15/2003; 112(2): 131-7. PMID: 12888329, PII: S002248040300088X, ISSN: 0022-4804.

Sotomayor RE, Washington M, Nguyen L, Nyang'anyi R, Hinton DM, Chou M. Effects of intermittent exposure to aflatoxin B1 on DNA and RNA adduct formation in rat liver: dose-response and temporal patterns. Toxicol. Sci [print-electronic]. 2003 Jun; 73(2): 329-38. PMID: 12700393, PII: kfg076, DOI: 10.1093/toxsci/kfg076, ISSN: 1096-6080.

Barton ES, Youree BE, Ebert DH, Forrest JC, Connolly JL, Valyi-Nagy T, Washington K, Wetzel JD, Dermody TS. Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease. J. Clin. Invest. 2003 Jun; 111(12): 1823-33. PMID: 12813018, PMCID: PMC161418, DOI: 10.1172/JCI16303, ISSN: 0021-9738.

Means AL, Ray KC, Singh AB, Washington MK, Whitehead RH, Harris RC, Wright CV, Coffey RJ, Leach SD. Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology. 2003 Apr; 124(4): 1020-36. PMID: 12671899, PII: S0016508503000647, DOI: 10.1053/gast.2003.50150, ISSN: 0016-5085.

Gray KD, Simovic MO, Chapman WC, Blackwell TS, Christman JW, Washington MK, Yull FE, Jaffal N, Jansen ED, Gautman S, Stain SC. Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis. J. Surg. Res. 2003 Mar; 110(1): 310-4. PMID: 12697416, PII: S0022480403000246, ISSN: 0022-4804.

Wudel LJ, Delbeke D, Morris D, Rice M, Washington MK, Shyr Y, Pinson CW, Chapman WC. The role of [18F]fluorodeoxyglucose positron emission tomography imaging in the evaluation of hepatocellular carcinoma. Am Surg. 2003 Feb; 69(2): 117-24; discussion 124. PMID: 12641351, ISSN: 0003-1348.

Rice PL, Washington M, Schleman S, Beard KS, Driggers LJ, Ahnen DJ. Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells. Cancer Res. 2003 Feb 2/1/2003; 63(3): 616-20. PMID: 12566304, ISSN: 0008-5472.

Limitations of histopathology in distinguishing high grade dysplasia and early adenocarcinoma in Barretts esophagus: an interobserver agreement study. Washington K [editorial]. Evidence Based Gastroenterology. 2003; 4: 37-8.

Washington K, Greenson JK, Montgomery E, Shyr Y, Crissinger KD, Polk DB, Barnard J, Lauwers GY. Histopathology of ulcerative colitis in initial rectal biopsy in children. Am. J. Surg. Pathol. 2002 Nov; 26(11): 1441-9. PMID: 12409720, ISSN: 0147-5185.

Washington K. Autoimmune cholangitis: not just AMA-negative primary biliary cirrhosis. Adv Anat Pathol. 2002 Jul; 9(4): 244-50. PMID: 12072815, ISSN: 1072-4109.

Wise PE, Wudel LJ, Belous AE, Allos TM, Kuhn SJ, Feurer ID, Washington MK, Pinson CW, Chapman WC. Biliary reconstruction is enhanced with a collagen-polyethylene glycol sealant. Am Surg. 2002 Jun; 68(6): 553-61; discussion 561. PMID: 12079138, ISSN: 0003-1348.

Crawford HC, Scoggins CR, Washington MK, Matrisian LM, Leach SD. Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J. Clin. Invest. 2002 Jun; 109(11): 1437-44. PMID: 12045257, PMCID: PMC150998, DOI: 10.1172/JCI15051, ISSN: 0021-9738.

Koay MA, Gao X, Washington MK, Parman KS, Sadikot RT, Blackwell TS, Christman JW. Macrophages are necessary for maximal nuclear factor-kappa B activation in response to endotoxin. Am. J. Respir. Cell Mol. Biol. 2002 May; 26(5): 572-8. PMID: 11970909, DOI: 10.1165/ajrcmb.26.5.4748, ISSN: 1044-1549.

Roberts RB, Min L, Washington MK, Olsen SJ, Settle SH, Coffey RJ, Threadgill DW. Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2002 Feb 2/5/2002; 99(3): 1521-6. PMID: 11818567, PMCID: PMC122223, PII: 032678499, DOI: 10.1073/pnas.032678499, ISSN: 0027-8424.

Washington K. Solid-pseudopapillary tumor of the pancreas: challenges presented by an unusual pancreatic neoplasm [editorial]. Annals Surg Oncol. 2002; 9: 3-4.

Washington K. Autoimmune cholangitis: not just AMA-negative primary biliary cirrhosis. Commentary on Autoimmune cholangitis within the spectrum of autoimmune liver disease. Czaja A.J., Carpenter H.A., Santrach P.J., Moore S.B., Hepatology, 2000, 31: 1231-1238. Advances in Anatomic Pathology. 2002; 9((6)): 244-50.

Wise PE, Shi YY, Washington MK, Chapman WC, Wright JK, Sharp KW, Pinson CW. Radical resection improves survival for patients with pT2 gallbladder carcinoma. Am Surg. 2001 Nov; 67(11): 1041-7. PMID: 11730220, ISSN: 0003-1348.

Williams CS, Sheng H, Brockman JA, Armandla R, Shao J, Washington MK, Elkahloun AG, DuBois RN. A cyclooxygenase-2 inhibitor (SC-58125) blocks growth of established human colon cancer xenografts. Neoplasia. 2001 Sep; 3(5): 428-36. PMID: 11687954, PMCID: PMC1506203, ISSN: 1522-8002.

Deane NG, Parker MA, Aramandla R, Diehl L, Lee WJ, Washington MK, Nanney LB, Shyr Y, Beauchamp RD. Hepatocellular carcinoma results from chronic cyclin D1 overexpression in transgenic mice. Cancer Res. 2001 Jul 7/15/2001; 61(14): 5389-95. PMID: 11454681, ISSN: 0008-5472.

Sheng H, Shao J, Washington MK, DuBois RN. Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J. Biol. Chem [print-electronic]. 2001 May 5/25/2001; 276(21): 18075-81. PMID: 11278548, PII: M009689200, DOI: 10.1074/jbc.M009689200, ISSN: 0021-9258.

Wolfe SG, Chey WY, Washington MK, Harding J, Heath AT, McSorley DJ, Dukes GE, Hunt CM. Tolerability and safety of alosetron during long-term administration in female and male irritable bowel syndrome patients. Am. J. Gastroenterol. 2001 Mar; 96(3): 803-11. PMID: 11280555, PII: S0002-9270(00)02419-9, DOI: 10.1111/j.1572-0241.2001.03626.x, ISSN: 0002-9270.

Kong FM, Anscher MS, Sporn TA, Washington MK, Clough R, Barcellos-Hoff MH, Jirtle RL. Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor (M6P/IGF2R) locus predisposes patients to radiation-induced lung injury. Int. J. Radiat. Oncol. Biol. Phys. 2001 Jan 1/1/2001; 49(1): 35-41. PMID: 11163495, PII: S0360-3016(00)01377-8, ISSN: 0360-3016.

Washington K, Debelak JP, Gobbell C, Sztipanovits DR, Shyr Y, Olson S, Chapman WC. Hepatic cryoablation-induced acute lung injury: histopathologic findings. J. Surg. Res. 2001 Jan; 95(1): 1-7. PMID: 11120627, PII: S0022-4804(00)95976-6, DOI: 10.1006/jsre.2000.5976, ISSN: 0022-4804.

[place unknown: publisher unknown]; 2001.

Washington K, Wright K, Shyr Y, Hunter EB, Olson S, Raiford DS. Hepatic stellate cell activation in nonalcoholic steatohepatitis and fatty liver. Hum. Pathol. 2000 Jul; 31(7): 822-8. PMID: 10923919, PII: S0046-8177(00)81677-9, DOI: 10.1053/hupa.2000.8440, ISSN: 0046-8177.

Chapman WC, Debelak JP, Wright Pinson C, Washington MK, Atkinson JB, Venkatakrishnan A, Blackwell TS, Christman JW. Hepatic cryoablation, but not radiofrequency ablation, results in lung inflammation. Ann. Surg. 2000 May; 231(5): 752-61. PMID: 10767797, PMCID: PMC1421063, ISSN: 0003-4932.

Lamps LW, Gray GF, Dilday BR, Washington MK. The coexistence of low-grade mucinous neoplasms of the appendix and appendiceal diverticula: a possible role in the pathogenesis of pseudomyxoma peritonei. Mod. Pathol. 2000 May; 13(5): 495-501. PMID: 10824920, DOI: 10.1038/modpathol.3880086, ISSN: 0893-3952.

Kong FM, Anscher MS, Washington MK, Killian JK, Jirtle RL. M6P/IGF2R is mutated in squamous cell carcinoma of the lung. Oncogene. 2000 Mar 3/16/2000; 19(12): 1572-8. PMID: 10734317, DOI: 10.1038/sj.onc.1203437, ISSN: 0950-9232.

Shattuck-Brandt RL, Varilek GW, Radhika A, Yang F, Washington MK, DuBois RN. Cyclooxygenase 2 expression is increased in the stroma of colon carcinomas from IL-10(-/-) mice. Gastroenterology. 2000 Feb; 118(2): 337-45. PMID: 10648462, PII: S0016508500564348, ISSN: 0016-5085.

Song SY, Gannon M, Washington MK, Scoggins CR, Meszoely IM, Goldenring JR, Marino CR, Sandgren EP, Coffey RJ, Wright CV, Leach SD. Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha. Gastroenterology. 1999 Dec; 117(6): 1416-26. PMID: 10579983, PII: S0016508599005648, ISSN: 0016-5085.

Blackwell TS, Debelak JP, Venkatakrishnan A, Schot DJ, Harley DH, Pinson CW, Williams P, Washington K, Christman JW, Chapman WC. Acute lung injury after hepatic cryoablation: correlation with NF-kappa B activation and cytokine production. Surgery. 1999 Sep; 126(3): 518-26. PMID: 10486604, PII: S0039606099002767, ISSN: 0039-6060.

Stutts JT, Washington K, Barnard JA. Cholestatic jaundice with skin desquamation in a 12-year-old girl. J. Pediatr. 1999 May; 134(5): 649-53. PMID: 10228305, PII: S0022-3476(99)70256-8, ISSN: 0022-3476.

Shao J, Sheng H, Aramandla R, Pereira MA, Lubet RA, Hawk E, Grogan L, Kirsch IR, Washington MK, Beauchamp RD, DuBois RN. Coordinate regulation of cyclooxygenase-2 and TGF-beta1 in replication error-positive colon cancer and azoxymethane-induced rat colonic tumors. Carcinogenesis. 1999 Feb; 20(2): 185-91. PMID: 10069452, ISSN: 0143-3334.

Lamps LW, Carson K, Bradley AL, Pinson CW, Johnson JE, Coogan AC, Hunter EB, Clavien PA, Washington MK. Pulmonary vascular morphological changes in cirrhotic patients undergoing liver transplantation. Liver Transpl Surg. 1999 Jan; 5(1): 57-64. PMID: 9873094, PII: S152764659900009X, ISSN: 1074-3022.

[place unknown: publisher unknown]; 1999.

[place unknown: publisher unknown]; 1999.

Lamps LW, Pinson CW, Raiford DS, Shyr Y, Scott MA, Washington MK. The significance of microabscesses in liver transplant biopsies: a clinicopathological study. Hepatology. 1998 Dec; 28(6): 1532-7. PMID: 9828217, PII: S0270913998004856, DOI: 10.1002/hep.510280613, ISSN: 0270-9139.

Roselli HT, Su M, Washington K, Kerins DM, Vaughan DE, Russell WE. Liver regeneration is transiently impaired in urokinase-deficient mice. Am. J. Physiol. 1998 Dec; 275(6 Pt 1): G1472-9. PMID: 9843786, ISSN: 0002-9513.

Chapman WC, Fisk J, Schot D, Debelak JP, Washington MK, Bluth RF, Pierce D, Williams LF. Establishment and characterization of primary gallbladder epithelial cell cultures in the prairie dog. J. Surg. Res. 1998 Nov; 80(1): 35-43. PMID: 9790812, PII: S0022-4804(98)95401-4, DOI: 10.1006/jsre.1998.5401, ISSN: 0022-4804.

Washington K, Chiappori A, Hamilton K, Shyr Y, Blanke C, Johnson D, Sawyers J, Beauchamp D. Expression of beta-catenin, alpha-catenin, and E-cadherin in Barrett's esophagus and esophageal adenocarcinomas. Mod. Pathol. 1998 Sep; 11(9): 805-13. PMID: 9758359, ISSN: 0893-3952.

Taga SA, Washington MK, Terrault N, Wright TL, Somberg KA, Ferrell LD. Cholestatic hepatitis C in liver allografts. Liver Transpl Surg. 1998 Jul; 4(4): 304-10. PMID: 9649645, PII: S1527646598000574, ISSN: 1074-3022.

Lamps LW, Hunt CM, Green A, Gray GF, Washington K. Alterations in colonic mucosal vessels in patients with cirrhosis and noncirrhotic portal hypertension. Hum. Pathol. 1998 May; 29(5): 527-35. PMID: 9596279, ISSN: 0046-8177.

Sheng H, Shao J, Williams CS, Pereira MA, Taketo MM, Oshima M, Reynolds AB, Washington MK, DuBois RN, Beauchamp RD. Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas. Carcinogenesis. 1998 Apr; 19(4): 543-9. PMID: 9600336, ISSN: 0143-3334.

Yan HP, Carter CE, Wang EZ, Page DL, Washington K, Wamil BD, Yakes FM, Thurman GB, Hellerqvist CG. Functional studies on the anti-pathoangiogenic properties of CM101. Angiogenesis. 1998; 2(3): 219-33. PMID: 14517462, PII: 188221, DOI: 10.1023/A:1009258801899, ISSN: 1573-7209.

McCauley J, Irish W, Thompson L, Stevenson J, Lockett R, Bussard R, Washington M. Factors determining the rate of referral, transplantation, and survival on dialysis in women with ESRD. Am. J. Kidney Dis. 1997 Dec; 30(6): 739-48. PMID: 9398116, PII: S0272638697002412, ISSN: 0272-6386.

Gao W, Washington MK, Bentley RC, Clavien PA. Antiangiogenic agents protect liver sinusoidal lining cells from cold preservation injury in rat liver transplantation. Gastroenterology. 1997 Nov; 113(5): 1692-700. PMID: 9352874, PII: S0016508597005386, ISSN: 0016-5085.

Washington K, Bentley RC, Green A, Olson J, Treem WR, Krigman HR. Gastric graft-versus-host disease: a blinded histologic study. Am. J. Surg. Pathol. 1997 Sep; 21(9): 1037-46. PMID: 9298880, ISSN: 0147-5185.

Washington K, Clavien PA, Killenberg P. Peribiliary vascular plexus in primary sclerosing cholangitis and primary biliary cirrhosis. Hum. Pathol. 1997 Jul; 28(7): 791-5. PMID: 9224746, ISSN: 0046-8177.

Mergener K, Washington MK, Pappas TN, Sharara AI. Benign gastric ulcer masquerading as a submucosal tumor. Endoscopy. 1997 May; 29(4): 331. PMID: 9255545, DOI: 10.1055/s-2007-1004204, ISSN: 0013-726X.

Carson K, Washington MK, Treem WR, Clavien PA, Hunt CM. Recurrence of nonalcoholic steatohepatitis in a liver transplant recipient. Liver Transpl Surg. 1997 Mar; 3(2): 174-6. PMID: 9346732, PII: S1527646597000282, ISSN: 1074-3022.

Kong FM, Washington MK, Jirtle RL, Anscher MS. Plasma transforming growth factor-beta 1 reflects disease status in patients with lung cancer after radiotherapy: a possible tumor marker. Lung Cancer. 1996 Dec; 16(1): 47-59. PMID: 9017584, PII: S0169500296006113, ISSN: 0169-5002.

Mantyh CR, Pappas TN, Lapp JA, Washington MK, Neville LM, Ghilardi JR, Rogers SD, Mantyh PW, Vigna SR. Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum. Gastroenterology. 1996 Nov; 111(5): 1272-80. PMID: 8898641, PII: S0016508596004829, ISSN: 0016-5085.

Procop GW, Harrell LJ, Washington MK, Owen CH, Pappas TN. Pericolic abscess due to Streptococcus pyogenes: report of a case that clinically mimicked acute cholecystitis. Clin. Infect. Dis. 1996 Jul; 23(1): 182-3. PMID: 8816152, ISSN: 1058-4838.

Clavien PA, Camargo CA, Cameron R, Washington MK, Phillips MJ, Greig PD, Levy GA. Kupffer cell erythrophagocytosis and graft-versus-host hemolysis in liver transplantation. Gastroenterology. 1996 Jun; 110(6): 1891-6. PMID: 8964415, PII: S0016508596002788, ISSN: 0016-5085.

Clavien PA, Camargo CA, Gorczynski R, Washington MK, Levy GA, Langer B, Greig PD. Acute reactant cytokines and neutrophil adhesion after warm ischemia in cirrhotic and noncirrhotic human livers. Hepatology. 1996 Jun; 23(6): 1456-63. PMID: 8675164, PII: S0270913996002340, DOI: 10.1002/hep.510230623, ISSN: 0270-9139.

Camargo CA, Washington MK, Fitz JG, Clavien PA. Adult presentation of diffuse bile duct stenosis: therapy with liver transplantation. Liver Transpl Surg. 1996 May; 2(3): 235-7. PMID: 9346654, ISSN: 1074-3022.

Bodily K, Perfect JR, Procop G, Washington MK, Affronti J. Small intestinal histoplasmosis: successful treatment with itraconazole in an immunocompetent host. Gastrointest. Endosc. 1996 May; 43(5): 518-21. PMID: 8726772, PII: S0016-5107(96)70300-0, ISSN: 0016-5107.

Telen MJ, Udani M, Washington MK, Levesque MC, Lloyd E, Rao N. A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding. J. Biol. Chem. 1996 Mar 3/22/1996; 271(12): 7147-53. PMID: 8636151, ISSN: 0021-9258.

De Souza AT, Hankins GR, Washington MK, Orton TC, Jirtle RL. M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nat. Genet. 1995 Dec; 11(4): 447-9. PMID: 7493029, DOI: 10.1038/ng1295-447, ISSN: 1061-4036.

Caniza MA, Granger DL, Wilson KH, Washington MK, Kordick DL, Frush DP, Blitchington RB. Bartonella henselae: etiology of pulmonary nodules in a patient with depressed cell-mediated immunity. Clin. Infect. Dis. 1995 Jun; 20(6): 1505-11. PMID: 7548500, ISSN: 1058-4838.

De Souza AT, Hankins GR, Washington MK, Fine RL, Orton TC, Jirtle RL. Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors. Oncogene. 1995 May 5/4/1995; 10(9): 1725-9. PMID: 7753549, ISSN: 0950-9232.

Boockvar KS, Granger DL, Poston RM, Maybodi M, Washington MK, Hibbs JB, Kurlander RL. Nitric oxide produced during murine listeriosis is protective. Infect. Immun. 1994 Mar; 62(3): 1089-100. PMID: 7509315, PMCID: PMC186228, ISSN: 0019-9567.

Eisen GM, Schutz SM, Washington MK, Burton CS, Sidhu-Malik N, Wilson JA. Atypical presentation of inflammatory bowel disease in the elderly. Am. J. Gastroenterol. 1993 Dec; 88(12): 2098-101. PMID: 8249980, ISSN: 0002-9270.

Sarasua MM, Faught KR, Steedman SL, Gordin MD, Washington MK. A comparison of ethanol partitioning in biological and model membranes: nonideal partitioning is enhanced in synaptosomal membranes. Alcohol. Clin. Exp. Res. 1989 Oct; 13(5): 698-705. PMID: 2688471, ISSN: 0145-6008.

[place, publisher, date unknown].

[place, publisher, date unknown].